Barnaby's cousin, a cop from Chicago comes and calls him, he tells Barnaby he has a lead on the man who killed his partner, whom he's been looking for. But after talking to him, some men grab him and kill him. Barnaby's informed of his death. He then calls his son, J.R. who comes and demands to know what is being done to find who killed his father. Barnaby thinks he has a lead but proceed cautiously. But J.R. is impatient and goes on his own.
A man supplying secrets to an investigative reporter is murdered in the desert by the hired henchman of a crooked land developer. Barnaby is hired to investigate to get to the bottom of it, but not before another murder is committed.
A grieving widow asks Barnaby to look into the death of her charter pilot husband who died on a run. During the investigation Barnaby and J. R. discover a family operated money smuggling ring with a black sheep son stealing from them.
Barnaby suspects foul play following the accidental deaths of a judge and a doctor, who both received alleged phone calls just prior to their demise from a dead woman whom they both helped put into a mental institution years before.
In order to clear an innocent man Barnaby races against time to find an escaped convict who's testimony can set him free. Also trying to find the same convict is a bounty hunter with a reputation for bringing his quarry in dead.
While investigating the intentional death of a nun's biological sister who was on life support, Barnaby uncovers a prostitution ring in which the deceased was a part of. The leading suspect is Sister Terry, but Barnaby doesn't buy it.
A young girl from a wealthy family runs away with a man saddled with gambling debts and she soon realizes that he is only after her fathers money. After witnessing a shooting he was involved in, she goes into hiding only to find more danger. Barnaby and J. R. race against time to find her before any harm can come to her.