Rich siblings Edward & Amanda are feuding over their late father's estate. Amanda is also suicidal since she is grief-stricken over her involvement in the death of her father & the disappearance of her sister. Edward hires Esther, a former nurse who has some dark secrets of her own, in order to watch over Amanda – and to ensure that if Amanda, who has a history of suicide attempts, tries to kill herself again, that she must succeed. As Edward secretly tries to kill Amanda due to her knowledge of their family's ill fortune, Esther discovers that the pair have been responsible for the fate of their family members.
This B-grade mystery thriller was notable for being released with a lurid poster which featured a woman in red negligee being pursued by hands that come from walls around her. The reality is that the film is nothing more than an average mystery thriller with some reasonably good acting.
Director Randall Hood did not live to see his film being released – he died of cancer while the film was still in post-production & a long-running rumour has it that Clint Eastwood had stepped in to oversee the production as a favour for actor Jack Ging.
As far as mystery thrillers go, Die Sister, Die! is okay, although not good enough to warrant more than one viewing. The actors do their roles professionally – Jack Ging has some fun in his role as the sinister brother who tries to get his fortune by killing his suicidal sister – and the production values are okay. But in saying that, Die Sister, Die! has nothing to say about the thriller genre other than to use the old 'feuding siblings' plot that has been around for a while. Inexplicably, the film was remade in 2013.