According to a New York Times article published in January 1973, director Gerard Damiano originally signed a deal that entitled him to one third of the profits. Damiano claimed he later sold his interest for $25,000, reputedly under pressure from partners involved in organized crime.
The film contains a number of references to the James Bond film series. The James Bond theme song can be briefly heard in the soundtrack. Dr Young refers to "case 007". At the time, Terence Young had directed most of the James Bond films.
The Radio Times "Guide to Films 2007" picked this as one of 100 landmark films of all time. Radio Times' film editor Andrew Collins said that the list is about a film's influence on society, not cinematic quality. Collins said "'Deep Throat' is not necessarily recommended for everyone. It's a quite badly made film, but to deny its influence would be pure snobbery."
Dutch public television aired the complete, uncut movie on February 23, 2008. It was the first time hardcore porn had been shown on Dutch public television. It led to discussion all the way up to parliament.