A marshal from New Mexico travels to New York City to deliver a witness who is supposed to testify in a murder trial. However, the witness is soon kidnapped from his custody, and in trying to get him back, the marshal finds that the case involves Puerto Rican nationalists, a lady novelist and a dead beauty queen, and a possible frame-up.
The horseback chase used in all subsequent episode titles caps this story of McCloud trying to track a drug thief who barely grazed him with a bullet, leading McCloud to believe the thief is an addict who can be helped.
McCloud welcomes several of his New Mexico cowboy buddies to Madison Square Garden for a rodeo, but winds up in a murder investigation when a young cowboy is slain and the most unpopular man in the West takes it on the lam -- even though he didn't do it.
When McCloud is summoned to JFK Airport by Chief Clifford, he finds Clifford held hostage by two crooks, one of whom keeps Clifford company at home while the second goes with McCloud on a pair of phony diplomatic passports to Paris, with this mission of concluding a secret business deal with smugglers. When McCloud gets out of the net, he and a friendly stewardess must track down the second thug and catch him before he can order Clifford murdered.