The segments "Eyes" and "The Escape Route" are based upon novellas Rod Serling wrote for the book "The Season to Be Wary" in 1967. Serling conceived of this series as a way to revive the anthology concept of Twilight Zone (1959) with a fresh spin. Initially the series was to be called "Rod Serling's Wax Museum."
The "Eyes" segment was Steven Spielberg's professional debut as a director. This was quite an auspicious beginning, considering that he was to direct screen legend Joan Crawford, winner of an Academy Award who had been acting in films since 1925.
In the first segment, in the scene in which Roddy McDowall shouts, "What in God's name is happening?" the sound track was faulty. During editing, McDowell was no longer available, so director John Badham himself looped the line.
Upon first meeting Steven Spielberg, Joan Crawford was less than impressed. She called Sid Sheinberg, then head of Universal Television, and told him to replace Spielberg with a better director or she would quit the series. Sheinberg told her in no uncertain terms that the studio would back Spielberg over her, as she had not acted on television in years and was at the time the Chairman of Pepsi-Cola, and Universal was confident in Spielberg's abilities. She subsequently treated him with the utmost respect, and the two continued to correspond until her death.
This is second of two Joan Crawford vehicles in which she plays a woman who undergoes surgery to regain her sight. In 1952's This Woman Is Dangerous, she played a similarly sight-impaired character who has a risky eye operation.