The mother of a young boy is a strong believer in a religious group called The Satan Fighters. When he becomes fatally ill, she believes he is being taken by his guardian angel to heaven and refuses medical treatment to allow this miracle to happen. Dr. Welby must do everything in his power to save the boy.
Life outside the ring - permanently - is not easy for Danny Williams, a promising young fighter who shields the fact that he is epileptic from his wife. Williams struggles with having to adjust to a new life, despite the best efforts of Welby, Kiley and Williams' wife, Laurie.
A young couple has a daughter who has unexplained attacks and keeps her hidden. Welby and Kiley diagnose her as having tortion dystonia, a disease similar to muscular dystrophy. The surgical process to releave her symptoms is shown.
Dr. Welby's patient dies in the night and her daughter agrees, under grieving duress, to a $5000 funeral. In the meantime, Dr. Kiley's long-time friend develops problems with his kidneys, and is unable to attend the opening of his art exhibit. Not to worry, Marcus Welby, M.D. is on both cases!
Kiley's medical and personal lives come into conflict after he takes Susan Davis (a former patient of his) out to dinner. Susan has been harassed by her ex-boyfriend, Wayne, who stalks her undeterred as Kiley repeatedly warns him off. On the night of Kiley's dinner date, Wayne breaks into Susan's apartment and attempts to rape her. Kiley runs in and scares Wayne off, then goes after him. As Kiley is going after Wayne (to get a license and car description so he can contact the police), Wayne loses control of his car and crashes into a concrete barrier, seriously ...
Kiley finds himself fighting for his medical career after Wayne Trent - the man who was stalking his ex-girlfriend, who was now dating Kiley - files a medical malpractice lawsuit against him, all in the aftermath of a car chase and subsequent accident in which Wayne was seriously injured.
Because his wife has chronic heart disease, a financial manager has a one-night stand with a model that gives him syphilis. The illness comes out in a routine physical and the results are both professionally and personally devastating.
A young man returns home after several years abroad to visit a high school friend only to find his him seriously ill and in a severe depression. In helping his friend, the man finds he has personal problems of his own to deal with.
A young teenage violinist appears to have a disease that only occurs in adolescents and Welby feels that he may be misdiagnosing because he is in shock over the death of an old friend earlier in the day.