Uncle Harry is hired to drive a motor home from Los Angeles to San Francisco, and foolishly agrees to take Lucy and the kids along for the ride. Lucy takes over driving so Harry can take a nap, and decides to take a detour, ending up visiting an air force academy in Colorado which Craig want to apply to after he graduates. Chaos ensues.
Lucy is still trying as hard as she can to get Craig into the Air Force Academy, and each result ends hilariously. This week she decides to camp out and gets the family captured as part of some war games.
While in Arizona for a picnic (on their way to San Francisco) the Carters borrow a raft which leads to misadventures of the wet & wild variety. After camping outdoors near a river, Lucy's mattress gets carried away with the current, with Kim, Craig, and Harry trying to rescue her.
Harry shares sad news with his family of a SERIOUS operation, which turns out to be having his tonsils out. Lucy, Kim, and Craig attempt to keep Uncle Harry in the hospital after Harry has a run in with the nurse (Mary Wickes). Once he meets the sexy nurse (Paula Stewart) he changes his mind and wants to stay.
Kim and her new boyfriend go to a drive in movie. Suspicious Lucy drags Harry to the drive in disguised as old hippies to spy on them. Of course Lucy and Harry cause such a stir at the drive in, it causes them to be kicked out.
Needing another means of transportation, Kim and Craig buy an old broken down car for 97 dollars from Cheerful Charlie, the local car salesman. When the car no longer works, Lucy and Harry scheme to get Charlie to take it back for more than it's worth.
Lucy sneaks Harry and the kids into a taping of The Tonight Show with Johnny Carson, wins an audience contest and gets to have a free dinner at the brown derby. When Lucy and Harry get to the restaurant, she sees Johnny and Ed Macmahon eating, and decide to horn in on their evening.
Kim and Craig are in charge of producing the school play, and decide its theme should be the Generation Gap. When they have casting problems, Lucy and Harry wind up playing the parents, and they all put on a really spectacular show.
The kids find a lost sheep dog and bring it home. After naming the sheep dog after Humphrey Bogart (Bogie), a litter of 9 puppies are born. After the puppies are giving to new homes, Uncle Harry arrives with a want ad offering a reward and they get all the puppies back.
Harry suggests Lucy is overworked and should hire an assistant. Suspecting Harry is really attempting to replace her, Lucy has Kim arrive to the office as temp secretary Shoiley Shopenauer, the world's worst office assistant.
Craig's high school club initiation scavenger hunt includes a candelabra that Craig borrowed from Liberace. Lucy of course thinks it has been stolen and feels obliged to return it to the famous pianist. A cute song and dance segment follows as the whole family end up with Liberace at his home.
Lucy brags to Viv, who's visiting, that she knows Lawrence Welk personally, and then schemes to introduce her to the band leader, whom she has actually never met. She and Mary Jane then attempt to foot Vivian with a wax dummy, but the kids get the real Lawrence Welk instead.
Craig decides he wants to be a songwriter much to the dismay of doctor loving Lucy. Craig writes Country Magic. Ann-Margret likes Craig's new song, and wants to duet with him on her upcoming television special.
Lucy schemes to help change a father's image of his son. Wally Cox appears as the son of Alan Hale. Lucy & Wally guard a warehouse and are successful in foiling a real robbery and soaking Harry in the process.
While in Las Vegas, Lucy and family return a lost horse to singer Wayne Newton. While there they decide to take jobs as ranch hands to earn spending money so they can see some Las Vegas shows. Kim & Craig join Wayne doing equestrian stunts while Lucy & Harry get to do the branding and clean-up.
One night Kim, Craig and Lucy find an old diary belonging to Lucy's great-grandmother and see that Harry's side of the family has owed their side of the family $10 for 100 years, with interest! The total comes to an incredible amount (over $145,000) and so Harry let's Lucy become the boss of the Employment Agency.... until they find out that later on in the diary it says that Harry's side of the family paid back the $10.