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Prescription: Murder (1968)

A psychiatrist uses a patient he is having an affair with to help him kill his wife, but his perfect alibi may come apart at the hands of a seemingly befuddled LAPD lieutenant.



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A psychiatrist who is married, is having an affair. His wife threatens to divorce him and take him to the cleaners if she ever catches him. So along with his mistress he plans to kill her and make it seem like she was killed by an intruder. He goes out of town as part of his plan and returns to find the police there investigating and the man investigating is Lt. Columbo. Columbo is a little odd and he asks the man some questions that he finds intrusive. Columbo continues to question him and the man's friend an ADA warns Columbo to watch his step. But Columbo goes on. Written by rcs0411@yahoo.com

Plot Summary | Plot Synopsis


The perfect crime had one flaw. See more »


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Release Date:

February 1968 (USA)  »

Also Known As:

Columbo: Prescription Murder  »

Company Credits

Production Co:

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Technical Specs


Sound Mix:



Aspect Ratio:

1.33 : 1
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Did You Know?


The role of Lt. Columbo was offered to Lee J. Cobb, but he had to decline due to a clash in scheduling. See more »


You can see stage lights shining on the view from the balcony, also revealing the balcony view as a backdrop. See more »


Dr. Ray Flemming: Are you sure of everything? Shall I do it over again?
Joan Hudson: No, I don't want to talk about it anymore!
Dr. Ray Flemming: Ah, but it will be fine, I promise you. Just pretend you're working on a role, right down to the props.
See more »

Crazy Credits

The beginning credits feature a series of brightly colored animated splotches. The splotches were mean to resemble the ink blots used in a Rorschach test, as the villain in this movie was a psychiatrist. See more »


Follows The Chevy Mystery Show: Enough Rope (1960) See more »

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User Reviews

"The pilot episode for the long running series stands as one of the best."
19 October 2003 | by (Poole, Dorset) – See all my reviews

A shabby detective called Columbo sets out to prove that a smooth talking doctor murdered his wife for his younger mistress.

The pilot episode for the long running series which began four years later. This probably stands as one of the best with good performances and a neat twist ending which many subsequent episodes lacked.

The film is based on Richard Levison & William Link's Broadway show which starred Thomas Mitchell as Columbo.

Prescription Murder has been released on video in the UK paired with the Dead Weight episode.

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