The Mole Man, out for revenge, lures the Fantastic Four to a deserted island. The Mole Man has constructed an elaborate tunnel system that can lower major cities of the world beneath the Earth's surface. The villain intends to eliminate the foursome so he can proceed with his plan.
In Transylvania, the Fantastic Four find a ruined castle. Ben is summoned by Diablo and unable to resist, opens Diabolo's prison, unleashing him and later brainwashing Ben. Diablo tricks the world into thinking he has the power to help them. The world then realizes what a fraud Diablo really is. The Fantastic Four seize this opportunity to attack Diablo's castle. After getting far in the dungeons, the four get captured. Ben escapes, releases the others and they defeat Diablo.
Reed is competing with Dr. Kragoff in race to the moon for astronomical research. During the launch, Dr. Kragoff and his primate crew have developed some reverse energy powers. Dr. Kragoff is now transparent. Dr. Kragoff kidnaps Susan after counter attacking. She escapes and thwarts Dr. Kragoff's attempt to eliminate her companions. Using a special device, Reed turns Dr. Kragoff into a plastic statue.
The Skrulls have failed to destroy the Fantastic Four. They introduce The Super-Skrull who possesses double power effects the Fantastic Four have. The Fantastic Four are overwhelmed by the Super-Skrull's combined powers. The Fantastic Four lure the Super-Skrull to Crater Island. Susan plants a sonic wave jamming device on the Super-Skrull before he can destroy them with his ultimate power level.
Dr. Doom challenges the Fantastic Four. Doctor Doom begins his plans by capturing Susan. Soon the Fantastic Four manage to locate and penetrate Dr. Doom's flying fortress, but Ben is turned back to his former self and the other three are trapped. Ben turns himself back into the Thing, releases the others and aborts Dr. Doom's tidal waves. They chase Dr. Doom out and back to the flying fortress. After a struggle through the dangerous complex of the fortress, they abort Dr. Doom's global destruction for good.
Reed recalls the time he first met Victor before he became Dr. Doom. Victor was working on a dangerous experiment that brought him to the hospital, got him expelled from university and badly altered his face and he swore revenge on Reed. Ben and Reed became soldiers in WWII. Ben, Susan, Johnny and Reed all went aboard a space rocket for space exploration. And so the origin of the Fantastic Four began. Dr. Doom confronts the Fantastic Four and briefs them on his origin. After that Dr. Doom attempts to get his revenge, but fails and escapes only to crash.
The Fantastic Four are testing their rocket when they are drawn into the Skrull Galaxy. After beating the first round of Skrulls, the Fantastic Four weaken and are taken prisoner. The cruel Skrull Warlord Morrat wishes to overthrow the Skrull Emperor. The Warlord gives the Fantastic Four the option to assist them or die. Reed tricks the Warlord into getting him and his friends' powers fully charged. They defeat the Warlord as the Emperor arrives and he allows the Fantastic Four to go freely back to Earth.
A UFO abducts the Fantastic Four from the Science Centre to Planet X. There, their dictator Kurrgo requests the Fantastic Four save their planet from another planet knocked off its orbit. Reed manages to formulate a working plan to save the population. While the plan is in process, Kurrgo has other ideas. However Reed tricks Kurrgo and leaves him on the exploding planet while the micro-sized population and the Fantastic Four get away to safety.
The Fantastic Four study a radiated meteor. The Molecule Man appears and threatens the public. After the Fantastic Four tastes some of his power, he leaves to undergo his ruling the world. Reed has developed a weapon he thinks will defeat the Molecule Man. The weapon works, but the Molecule Man gets away. The Fantastic Four continue their pursuit. The plan to stop the Molecule Man is tricky. They manage to reverse the Molecule Man's form with a fragment of the meteor.
Professor Gamma, a mad scientist mutated into a fish-man by the radioactive undersea rubble of what had been his base until it was destroyed by the Fantastic Four, seeks vengeance with his new-found powers as the Gamma Ray.
The Mole Man is creating earthquakes and causing buildings to sink deep into the Earth. In addition, he and his Moloids kidnap Susan. The Mole Man as usual has been expecting the other three and sends them back to the surface to tell the Army not to get involved. They manage to halt them and seek an alternate entrance in the underworld. Johnny rescues Susan, then they penetrate the laboratory. They all return the buildings to the surface and escape the exploding caves.
Galactus, a powerful being who devours planets for their energy, is coming to Earth. He is preceded by his herald, the Silver Surfer. The Watcher, another powerful being who is not allowed to take direct action, helps the Human Torch travel to Galactus's home base. Meanwhile, the FF convince the Surfer to take their side in the confrontation with Galactus. The FF fight Galactus to a standstill after the Torch brings the "ultimate nullifier" back from Galactus's home base. After Galactus departs, the Surfer also leaves to soar through the vastness of space. The episode...
A challenge from The Thing haters, The Yancy Street Gang, to the entire Fantastic Four turns out to be a forgery from The Red Ghost, who kidnaps the heroes to the moon for a revenge-fueled battle between the Four and him & his three super-powered apes.
On a remote planet, its inhabitants are fighting against Blastaar and are able to banish him. Reed and Johnny enter the dangerous space zone via dimensional transport. As they depart, Blastaar escapes and follows them. Blastaar is too powerful for the four to handle. They lure Blastaar into an evacuated atomic power plant, where they use some atomic matter to put him in a coma. They eject him through the dimensional transport back into the space zone.
After coming back from vacation Reed tells Ben an interesting theory on attempting to restore him. They head to Dr. Doom's deserted castle to use the time machine the doctor left behind. In 2000 B.C the four weaken during a fight and are taken by Pharaoh Rama-Tut. Susan is to be Rama-Tut's queen while the other three are put to work with some mind control. Ben turns back to his former self. As he rescues Susan he is once again the Thing. The four battle Rama-Tut to his sphinx. Finally they destroy his sphinx and return to their own time.
The Fantastic Four are taken to another planet where they are regarded as criminals against evil, charged by three old enemies. Reed is forced to recall his memories on Klaw, Molecule Man and Blastaar's defeat. Meanwhile the other three escape and they rescue Reed just as the verdict is given. At the surface, they have to battle the court judge before they are able to leave the planet for Earth.
The Imposter plans to lure the Fantastic Four into a trap by posing as a famous Hollywood director. The four are tempted to be in a movie and briefly retell their previous adventures to the director. The next day, the four fly to the director's island and the director blows them out of the sky. The Fantastic Four are forced to go through the director's deadly movie landscapes and make it to the boat on the other side of the island which the director detonates. The Imposter removes his disguise and the Fantastic Four surprise him. The real director prevents the ...