The shock wave from an approaching comet is expected to detonate a missing nuclear bomb. Unfortunately for the Science Patrol, the bomb is located inside one of three different monsters. The Science Patrol must dispatch the three monsters without allowing the nuclear bomb to detonate.
Scientists capture a monster in order to put in on display at the World's Fair. Their attempt fails and the monster is on the loose. After the monster begins tunneling underground, the Science Patrol must track its location so they can prevent it from harming nearby populated areas.
A monster with the ability to blind it's victims, and the ability to become stronger after being attacked, begins wreaking havoc. Science Patrol member Arashi gets into trouble when he defies orders to leave the monster alone.