After being unexpectedly attacked by a lioness at Wameru, a retired boxer turned game hunter gets a permit to track her down and kill her. But Tracy is determined to find the lioness first and discover the reason for her strange behavior.
Dr. Tracy installs an electronic alarm system to protect more than $1 million worth of vaccine. Judy, angry that she's lost her job as guard, leads a protest against the new system that's replaced her.
When Judy douses Toto with elephant scent to test its value as a repellent to predators, it inadvertently leads to a tribal chief and medicine man becoming convinced that the baby chimp is the reincarnation of their god.
Dr. Tracy agrees to operate on a lion hunter's dog to remove a malignant tumor. But the rest of his staff is reluctant, particularly Paula, who thinks the dog, who injured Clarence, will just continue to kill lions.
Judy the chimp befriends an ailing lion who is brought into Wameru. She keeps sneaking food to the lion after he is released, even though he is suspected by tribesmen of being the lion who has been killing their cattle.
Paula, Jack, and Mike find their German shepherd Prince near death in the field from a poacher's spear. Because trying to move him could kill him, they are forced to try to remove the spear in the wild, without Dr. Tracy's help.
Dr. Tracy and a hunter compete to find a lioness who is accused of attacking a villager, each agreeing that whoever finds her will do what they intend. A seven-year-old orphan, who hopes to stay at Wameru, is riding along with Tracy.
A young American from a wealthy family says he wants to learn survival skills and comes to Wameru and goes out with Mike and Bart to observe the lions. But he has a romanticized view of how nature should be and is upset when it doesn't conform to it. He also has other motives for his trip.
A new neighbor, a rancher from Wyoming, plans to buy more property around Wameru and fence it off, which will create a major problem for migrating animals. He also wants to use the area inside the fences for charging tourists to hunt animals, despite the objections of the Wameru staff.
A young man is banished from his tribe after he refuses to take on his father's role as the village storyteller. Ignoring Dr. Tracy's advice, he places himself in mortal danger in order to prove that he can be a great warrior.
While out with a husband-and-wife team of photographers, Jenny and Judy discover a cave with possibly significant archaeological artifacts. But the wife of the photography team, ambitious to get her husband recognized, hopes to insure that only they get credit for the discovery.