Besides Don Knotts, there are a number of actors from the Andy Griffith Show in this movie, some playing characters very similar to the characters they did in the Andy Griffith Show. For example, Hal Smith plays the town drunk in both productions, and Dorthy Neumann plays Smith's wife in both productions. Also, "Griffith" show veterans, such as Burt Mustin and Hope Summers are featured in this movie. This was Knott's first film after leaving the Andy Griffith Show.
The "Simmons Mansion" was next door to the Munster Mansion on the Universal backlot and can be seen minus the fence in the opening credits of "Munster, Go Home" (1966). The Munsters house however cannot be seen in "The Ghost and Mr Chicken".
The car Luther Heggs drives is a 1959 Edsel Corsair, a short lived marque of the Ford Corporation named after Henry Ford's son, Edsel Ford. That car was a colossal failure, which would have been familiar to the audience of the time, and thereby reinforce Luther's image as a lovable loser.
The Houses in the film were made for the 1946 movie, "So Goes My Love". In 1950 they were moved to Colonial Street and then moved again to the new Colonial Street in 1981. The streets have been used in such TV shows as "Leave It To Beaver" (1957-63) "The Munsters" (1964-66) "Marcus Welby" (1969-76) "The Rockford Files" (1974-80) "Buffy The Vampire Slayer" (1997-03). It was also used in the movies "The Shaggy Dog" (1959) "Dragnet" (1987) The 'Burbs (1989) "The Ladykillers" (2004).
One of the few American films shot in the Technicolor Corporation's Techniscope wide screen process. The wide screen effect was achieved by essentially splitting the usual film frame horizontally into two smaller frames with a greater width to height ratio. It was inexpensive, but yielded a grainy image, which probably explains why it was seldom used in Hollywood.
All of the actors from this film have passed away with the exception of Joan Staley, Ellaraino, and Adair Jameson who are the three female survivors and Skip Homeier, Jimmy Bracken, and Teddy Quinn who are the three male survivors.
When the first story in the "Rachel Courier Express" newspaper, that was written by Luther Higgs (Don Knotts character ) is shown on screen, the news columns room the left and right are the same story, word for word, but offset slightly in starting position, so the story on right appears longer. The story on the right continues, while an article about the Hospital Fund Drive is below the story on the left.