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Followed by 

Remade as 

Lost in Space (1998)

Edited into 

Referenced in 

Laverne & Shirley: Lost in Spacesuits (1982)
title reference
U2: Unforgettable Fire (1984)
One person refers to another as being "Lost in Space" then saying "remember that show?"
The Best of John Belushi (1985)
Referenced in The last voyage of the Starship Enterprise
The Sure Thing (1985)
Gib says, "Danger, Will Robinson, Danger"
Demented Top 20 Video Countdown (1988)
Dr. Demento mentions this show.
Space Quest III: The Pirates of Pestulon (1989)
The Jupiter 2 can be seen in the garbage freighter's junkyard.
Mystery Science Theater 3000: Gamera vs. Guiron (1989)
Crow (as a spaceship flies on the screen): "It's the Robinson family!"
Mystery Science Theater 3000: Humanoid Woman (1989)
Servo: "Danger, Will Robinson!"
Mystery Science Theater 3000: Mighty Jack (1989)
Crow: "The robot in 'Lost in Space' - now *that* was funny!"
Mystery Train (1989)
Tales from the Crypt: Television Terror (1990)
mentioned in dialogue
Mystery Science Theater 3000: Rocketship X-M (1990)
Tom Servo quotes the Robot of this show while his voice box was changing.
Mystery Science Theater 3000: Catalina Caper (1990)
Crow: (as Dr. Smith) Oh, the pain, the pain.
Tiny Toon Adventures: Sawdust and Toonsil (1990)
Gogo says, "Danger, Will Robinson! Danger!"
Mystery Science Theater 3000: Wild Rebels (1990)
Crow (as Dr. Smith): "Oh, the pain! The shame!"
Mystery Science Theater 3000: King Dinosaur (1990)
Crow (as Dr. Smith): "Oh, the pain! The pain!"
Mystery Science Theater 3000: First Spaceship on Venus (1990)
Crow (as Dr. Smith): "Oh, the pain! The pain!"
The Toxic Crusaders: The Making of Toxie (1991)
Toxie: "Have no fear! Toxie's here!"
Parker Lewis: Jerry: Portrait of a Video Junkie (1991)
Referenced in Parker's narration
Mystery Science Theater 3000: The Amazing Colossal Man (1991)
Crow (as Dr. Smith): "Oh, the pain! The pain!"
Mystery Science Theater 3000: Earth vs. the Spider (1991)
Crow (as Dr. Smith): "The pain! The pain!"
Mystery Science Theater 3000: Viking Women vs. the Sea Serpent (1991)
Crow (as Dr. Smith): "Oh, the pain! The pain!"
Mystery Science Theater 3000: Santa Claus Conquers the Martians (1991)
"These are like cheap versions of the 'Lost in Space' sets."
Star Trek: The Next Generation: Conundrum (1992)
When Commander Will Riker is playing chess, one of his pieces is the Robinson's Robot.
Nurses: Catch a Fallen Star (1992)
Julie talks about watching "Lost in Space" when she was young.
Mystery Science Theater 3000: Manhunt in Space (1992)
Joel: "Yes, it's Dr. Smith and Mr. Mooney as you've never seen them before!"
Mystery Science Theater 3000: The Day the Earth Froze (1993)
Crow (as Dr. Smith): "Oh, the pain! The pain!"
Under a Killing Moon (1994)
Mentioned by Tex.
King of the Airways (1994)
Louis mentions the television show.
The Magic School Bus: Gets Lost in Space (1994)
The episode title and when the kids cry "We're lost in space!" are references to the classic sci-fi.
Mystery Science Theater 3000: The Creeping Terror (1994)
Servo: Danger, Will Robinson
Aladdin: When Chaos Comes Calling (1994)
Genie transforms into a robot calling "Warning, warning, Will Robinson".
The Nanny: The Strike (1994)
Fran mentions the character, Will Robinson.
Mystery Science Theater 3000: High School Big Shot (1994)
Mike: "I'll become Dr. Smith!"
The Critic: All the Duke's Men (1995)
June Lockhart says Duke promised her he would bring back everyone lost in space
Married with Children: The Undergraduate (1995)
Kelly: "But as the Chinese philosopher Unconscious once said: It's better to have loved and lost than to have never seen 'Lost in Space' at all."
Bio-Dome (1996)
Romulus says, "The horror! The pain!"
Big Bully (1996)
Freakazoid!: Mission: Freakazoid (1996)
Prof. Jones has been asked several times in the episode if he was from a show with a talking robot.
The Simpsons: The Twisted World of Marge Simpson (1997)
The robot flails it's arms and shouts Danger! Danger! like the robot from this show famously did.
The Nanny: The Bank Robbery (1997)
C.C. speaks of the TV show being turned into a movie.
Mystery Science Theater 3000: The Mole People (1997)
It's a pride of Dr. Smiths!
Mystery Science Theater 3000: Invasion of the Neptune Men (1997)
Crow: I just know Dr. Smith is going to be in this.
Siskel & Ebert: Lost in Space/The Spanish Prisoner/Mercury Rising/Kurt & Courtney/Character (1998)
Gene Siskel mentions the TV series in his review of the movie adaptation.
Siskel & Ebert: The Newton Boys/Meet the Deedles/A Price Above Rubies/No Looking Back (1998)
Roger Ebert says that next week's show will review the big screen version of this TV series.
Gex 64: Enter the Gecko (1998)
One of Gex's catchphrases is "Danger, Will Robinson."
Family Matters: Lost in Space: Part 1 (1998)
title reference
Family Matters: Lost in Space: Part 2 (1998)
title reference
One True Thing (1998)
George quotes the show/film
The Simpsons: The Wizard of Evergreen Terrace (1998)
When Homer imagines his funeral, the robot from "Lost in Space" is present.
A Bug's Life (1998)
At one point Manny cries out "the pain! the pain!", which was a Dr Smith expression from "Lost in Space".
The Simpsons: Mayored to the Mob (1998)
Dr. Smith is at the con signing autographs and the Robot is with him.
Hollywood Screen Tests: Take 2 (1999)
"Hollywood Screen Tests, Pt. 2" features many movies and tv shows in reference to the stars featured.
Saturday Night Live: Gwyneth Paltrow/Barenaked Ladies (1999)
Referenced in 'doing voices' skit
Family Guy: I Never Met the Dead Man (1999)
Peter sees the robot from Lost in Space in his dream.
Futurama: Love's Labours Lost in Space (1999)
title is a reference
Mystery Science Theater 3000: Blood Waters of Dr. Z (1999)
Dr. Z says, "The pain!", after which Tom adds, "Jonathan Harris would sue."
The Simpsons: Treehouse of Horror X (1999)
The robot from this show is among The Collector's kidnapped people.
Boom! Hollywood's Greatest Disaster Movies (2000)
Footage of his series is shown
Farscape: Nerve (2000)
Crichton whispers "Danger, Will Robinson," the famous Robot quote, before passing out
CSI: Crime Scene Investigation: Fahrenheit 932 (2001)
Sarah Sidle says,"Danger, Will Robinson."
Sonic Adventure 2 (2001)
A poster can be seen in one level advertising a movie called "Chao in Space". It's a parody of this show, the original font is used too.
Gilmore Girls: The Ins and Outs of Inns (2001)
Uses the quote "Danger Will Robinson! Danger!"
I Am Sam (2001)
"Danger, Will Robinson. Danger."
The X-Files: Jump the Shark (2002)
Referenced in dialogue.
The West Wing: 20 Hours in America (2002)
Josh says "Danger, Will Robinson."
Thirteen (2003)
The Simpsons: Hit & Run (2003)
The robot from this show is in Comic Book Guy's shop.
The Simpsons: Treehouse of Horror XIV (2003)
The robot from Lost in Space is in the background of Frink's lab.
Tripping the Rift: All for None (2004)
Bob yells 'Danger, Will Robinson'
Who's Your Daddy? (2004)
"Danger, Will Robinson!"
Gilmore Girls: A Family Matter (2004)
While warning Rory about Jess staying in town for the weekend, Lorelai quotes the show's famous "Danger, Will Robinson" line.
Surge of Power (2004)
Bob May is introduced as Robot from this show
Saturday Night Live: The Best of John Belushi (2005)
Referenced in The last voyage of the Starship Enterprise
The Sci-Fi Boys (2006)
A collection of Robot B9 toys seen with a collection of Robbie the Robot toys.
Dancing with the Stars: Episode #6.4 (2007)
When Daryl Somers reminds Tim Campbell that in the previous episode the judges wanted him to show some more danger, Tim says "Danger, Will Robinson" in a voice like the robot from this title.
Meet the Robinsons (2007)
The Robot shouts "Danger, Will Robinson" in "Lost in Space."
Doctor Who: Planet of the Ood (2008)
When Mr. Halpen and his group arrive on the planet and are first entering the building, the Jupiter 2 spaceship is seen in the background.
Just In with Laura Ingraham: Episode dated 18 June 2008 (2008)
This TV show is referenced by name.
Hole in the Wall: Actors vs Reality Stars (2008)
During their opening interview, one of the Reality Stars team members mentions that he feels like he's come off the Lost In Space set.
The Big Bang Theory: The Barbarian Sublimation (2008)
When awakened, Sheldon calls out, "Danger. Danger."
Top Gear Australia: The Practical Supercar (2008)
Mentioned in a discussion on a new Honda hybrid car.
King of the Hill: Lost in MySpace (2008)
Episode title
Wizards of Waverly Place: Wizards & Vampires vs. Zombies (2009)
A Character says 'Danger, Danger Will Robinson'
How I Met Your Mother: The Rough Patch (2009)
Actor in robot costume says lines from the robot in the show ("Danger, Will Robinson!").
Planet 51 (2009)
Chuck marches around saying "Crush, Kill, Destroy", a quote for an alien robot
Family Guy: And Then There Were Fewer (2010)
Brian hums the theme song for Stewie.
Hollywood Treasure: Let the Bidding Begin (2010)
Lost In Space props are shown and auctioned off.
Jeopardy!: Episode #27.62 (2010)
Question catagory title "Lost in Space"
Family Guy Presents: It's a Trap (2010)
Will Robinson is shot by the Death Star while Robot and Dr. Smith watch
Pioneers of Television: Science Fiction (2011)
Irwin Allen is a pioneer of science fiction television with "Lost in Space".
RuPaul's Drag Race: Queens in Space (2011)
Title reference.
Portlandia: Mayor Is Missing (2011)
(newspaper article title) "Lost in Bass?"
NCIS: Kill Screen (2011)
"Danger Will Robinson" quote by McGee. Maxine then says she loves that show.
Sonic Generations (2011)
A poster can be seen in one level advertising a movie called "Chao in Space 3". It's a parody of this show, the original font is used too.
Futurama: Möbius Dick (2011)
The Jupiter II is seen in the space-ship graveyard.
Star Wars XXX: A Porn Parody (2012)
Robot is in the Jawa's droid line-up

Featured in 

The Haunted (1991)
Kids are watching an episode on TV
Jack the Bear (1993)
on television
Science Fiction: A Journey Into the Unknown (1994)
clips from this show are in this special
Star Kid (1997)
Ms. Holloway watches it at home.
Biography: Al Lewis: Forever Grandpa (2000)
Documentary about a star of this series
Svengoolie: Svengoolie's TV Graveyard: Lost in Space Pilot, Found! (2006)
Episodes from this tv show were featured.
20 to 1: Greatest TV Families (2009)
Clips shown in a segment on the Robinson Family.

Spoofed in 

Dead End (1985)
quotes from the show, including "Warning Will Robinson, warning!"
Space Ghost Coast to Coast: Spanish Translation (1994)
Zorak says, "Danger! Danger!"
The Simpsons: Fear of Flying (1994)
Marge has a dream where she's the mother from this show.
Mystery Science Theater 3000: Time Chasers (1997)
Mike says they are lost in space! The 'bots take it literally!
Whose Line Is It Anyway?: Show No. 107 (1998)
Ryan imitates the robot from the show in Props.
Family Guy: Fore, Father (2000)
Parodies the ways in which the father and leader of the expedition send his children off with strange characters on dangerous missions
The Chubbchubbs! (2002)
The Robot is dancing in the bar.
Banjo-Kazooie: Nuts & Bolts (2008)
Level intro to Terrarium of Terror is a parody of Lost in Space's intro.
Family Guy: Episode VI: It's a Trap (2011)
Will Robinson is blasted by the Death Star while floating in space with Dr. Smith and The Robot

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