Erskine and Daniels investigate a St. Louis trucking company. The Organization uses trucks from the company to hijack shipments from other trucking firms. The Organization also takes a cut of the profits of the St. Louis company, which gains more and more business as its competitors are driven out of business. The owner of the St. Louis company begins to crack under the pressure and seeks a meeting with Erskine -- a meeting the Organization will seek to stop.
Selkirk, a former Army officer, is bitter that he was never promoted beyond major. He breaks out two prisoners from the stockade of an Army base in Arizona. As Erskine and Daniels investigate, it's clear that Selkirk has an impressive collection of weapons. The two prisoners were labeled "incorrigibles" by the Army and their expertise includes demolition. Selkirk's target is a $750,000 Army payroll -- and he has the means and the intelligence to pull off the job.
Frankie Geller escapes from a federal prison in Pennsylvania. Geller had agreed to take the rap for the Pittsburgh arm of the Organization in return for his family being taken care of. But that didn't happen and his wife killed herself. Geller now is seeking revenge and wants to expose Organization secrets. His primary target is Price, the Organization leader who led the double cross. Erskine and Daniels lead the FBI's manhunt for Geller and are racing to find him before the mob does.
Ben Sillman, an East Coast hitman nicknamed the Animal, pulls off an escape from a federal courthouse, where he is being tried for income tax evasion. He shoots two federal marshals. Erskine and Daniels head up the FBI's manhunt, working with Tom Colby, Erskine's former partner who now agent in charge of the bureau's west coast office. Sillman is on the outs with the East Coast mob and tries to force a West Coast mobster to help him flee the country. Complicating the FBI's search is the fact Sillman has kidnapped a woman for possible leverage.
Erskine and Daniels are on the trail of a gang that has stolen $20 million in travelers checks. The gang has been promised 10 percent, or $2 million, upon delivery to a fence. The fence, however, will now only pay $500,000. The gang's leader has other ideas. The FBI tries to catch up to the gang before the travelers checks can be transported to Hong Kong.
Danzer, a self-described "nobody," has pulled off a stunning theft of diamonds. He is on the run from Becker, hired by the owners of the stones. Danzer steals a plane but is forced to crash land after a gunshot from Becker has pierced the fuel tank of the airplane Danzer has stolen. Danzer, desperate, kidnaps a blind woman as he attempts to flee the United States. Erskine and Daniels lead the FBI's investigation, seeking to apprehend Danzer before he can get into Mexico. The FBI men are racing Becker to get there first. Becker has his own ideas what to do with the ...
Ernie Cahn leads a holdup of an armored car near Detroit. Cahn and his confederates had first stolen explosives from a National Guard armory which they then used in the heist. But Cahn, brash and arrogant, traits that will prove his undoing. Erskine and Daniels lead the bureau's hunt for Cahn. But Cahn may not survive long enough to be apprehended by the FBI. Cahn's employers have concluded he's a liability and plan to have to him killed.
Erskine and Daniels pursue Greg Jennings, who escaped a federal prison just one year before his five-year term was up. Jennings was convicted of trying to blackmail a congressman. It turns out that the blackmail plan was devised by Mason Hammond, a prominent columnist and author, as a way to get out from under his gambling debts. Jennings wants revenge on Hammond and is determined to get it.
Rudy Keppler, a New Orleans mob boss, has been hiding in Haiti for a year after rivals tried to kill him and murdered his brother Richie. Keppler now decides to return to the U.S. to avenge his brother's death. Erskine and Daniels are assigned by the bureau as Keppler arrives and a struggle ensues for control of the New Orleans branch of the Organization.
In Maryland, a woman graduate student is stabbed and is in serious condition. Because of the crime occurred on U.S. government-owned property, the FBI launches an investigation. Two other students at the same college were slain previously and all three victims belonged to the same sorority. Erskine and Daniels take charge and are joined by a woman FBI agent who graduated from the same college and belonged to the same sorority. The FBI has three suspects and the woman FBI agent will be endangered before the case is concluded.
Erskine and Daniels spearhead the FBI's manhunt for Belson, an escaped federal prisoner. Erskine captures Belson but, just before that, Daniels is critically injured because of a high fall. The Jeep and the radio of the FBI men has been disabled because of rifle shots fired by Belson. Erskine, miles from the nearest town, must try to bring in Belson while keeping Daniels alive. The devious Belson bides his time, waiting for the right time to strike.