 | Eddie Little Sky | ... | Chief Blackfish / ... (4 episodes, 1963-1964) |
 | Kent Smith | ... | General Nelson Miles / ... (4 episodes, 1963-1964) |
 | Ricardo Montalban | ... | Philip Crow / ... (3 episodes, 1963-1964) |
 | John Anderson | ... | Andrew Jackson / ... (2 episodes, 1963-1964) |
 | Arthur Batanides | ... | Gomez / ... (2 episodes, 1963-1964) |
 | Walter Brooke | ... | James Townsend / ... (2 episodes, 1963-1964) |
 | Russell Collins | ... | Tobacconist / ... (2 episodes, 1963-1964) |
 | Leif Erickson | ... | Abel Parrish / ... (2 episodes, 1963-1964) |
 | Ken Lynch | ... | Brown / ... (2 episodes, 1963-1964) |
 | Gene Lyons | ... | Dr. Aspenwall / ... (2 episodes, 1963-1964) |

| James MacArthur | ... | Lieutenant Alexander / ... (2 episodes, 1963-1964) |
 | John McGiver | ... | General Claiborne / ... (2 episodes, 1963-1964) |

| Carroll O'Connor | ... | Johann Sutter / ... (2 episodes, 1963-1964) |
 | Maxwell Reed | ... | Captain Lockyer / ... (2 episodes, 1963-1964) |

| Marion Ross | ... | Etta Wheeler / ... (2 episodes, 1963-1964) |
 | Barry Sullivan | ... | E.J. Edwards / ... (2 episodes, 1963-1964) |
 | Torin Thatcher | ... | Colonel Lewis Washington / ... (2 episodes, 1963-1964) |
 | Harry Townes | ... | Dr. O'Reilly / ... (2 episodes, 1963-1964) |
 | Bill Walker | ... | Charlie (2 episodes, 1963-1964) |
 | Ian Wolfe | ... | Brewer / ... (2 episodes, 1963-1964) |
 | Rodolfo Acosta | ... | Lieutenant Bullhead (2 episodes, 1963) |
 | Claude Akins | ... | Father Kranz (2 episodes, 1963) |
 | Noah Beery Jr. | ... | Jervis (2 episodes, 1963) |
 | Anthony Caruso | ... | Sitting Bull (2 episodes, 1963) |
 | Miriam Colon | ... | Sarah Crow (2 episodes, 1963) |
 | Joseph Cotten | ... | Captain Meehan (2 episodes, 1963) |
 | James Dunn | ... | Indian Agent McLean (2 episodes, 1963) |
 | Byron Morrow | ... | General Beauregard / ... (2 episodes, 1963) |
 | Lloyd Nolan | ... | Colonel Fraser (2 episodes, 1963) |
 | Stuart Cooper | ... | Flanders Callaway (2 episodes, 1964) |
 | Ken Drake | ... | Boatman (2 episodes, 1964) |
 | Andrew Duggan | ... | Colonel Callaway (2 episodes, 1964) |
 | Ted Eccles | ... | James Boone (2 episodes, 1964) |
 | Peter Graves | ... | Daniel Boone (2 episodes, 1964) |
 | Arthur Hunnicutt | ... | Simon Kenton (2 episodes, 1964) |
 | Frances Karath | ... | Elizabeth Callaway (2 episodes, 1964) |
 | Richard Lupino | ... | Lieutenant Brown (2 episodes, 1964) |
 | John Marley | ... | Callum / ... (2 episodes, 1964) |
 | David McCallum | ... | Captain Hanning (2 episodes, 1964) |

| Peggy McCay | ... | Mrs. Callaway (2 episodes, 1964) |
 | Laurie Mock | ... | Frances Callaway (2 episodes, 1964) |
 | Judee Morton | ... | Jemina Boone (2 episodes, 1964) |
 | James Westerfield | ... | Fletcher / ... (2 episodes, 1964) |
 | David White | ... | John C. Calhoun (2 episodes, 1964) |

| H.M. Wynant | ... | District Attorney / ... (2 episodes, 1964) |
Was this show only on for one season? That amazes me because I still remember many of the episodes so vividly. I was about 10 years old when "The Great Adventure" was on television and I always wondered why my history classes in school couldn't be this engrossing. I still remember the farms on the western plains being attacked by swarms of locusts, a young Andrew Jackson being struck by a British officer's sword, the founding of the Society for the prevention fo Cruelty to Children", and the claustrophobic feeling inside the USS Monitor. Why don't they have programs like this today? Why don't they run this series again on TVLand?