It is commonly given that this show was based on the Samuel Sheppard
murder case of 1954. While the show does feature some similarities to the case, Roy Huggins
consistently denied that he based Richard Kimble on Sheppard or the fictional murder on the real one. Claiming that he was unfamiliar with the Sheppard case until the series began, he said the show was actually influenced by his love for Westerns, and he wanted to do a series about a modern character roaming around the country in a similar fashion to a mythic cowboy. See more
The Fugitive, a QM Production, starring David Janssen as Dr. Richard Kimble, an innocent victim of blind justice, falsely convicted for the murder of his wife, reprieved by fate when a train wreck freed him en route to the death house; freed him to hide in lonely desperation, to change his identity, to toil at many jobs; freed him to search for a one-armed man he saw leave the scene of the crime; freed him to run before the relentless pursuit of the police lieutenant obsessed with his capture.