After he saves Trampas The Virginian hires a temporary hand full time. He seems to be the ideal hand but a loner until a man and woman are killed in Medicine Bow and he shoots Trampas. Garth realizes there may be two personas to the man.
A lost Betsy finds a man and his son living isolated in the mountains catching and breaking horses. They have a secret history that she tries to keep hidden but events force her and others into actions that may send the man to the gallows.
Ryker receives a clue as to the location of a man he wants for a murder two years ago. He goes on the trail but is forced to guide a young woman looking for her dad but both men may have been killed in an Indian massacre at Cripple Creek.
The Virginian rescues a passenger after they are in an accident near Shiloh but she has amnesia afterwards. He takes a deep interest in her even after she moves in with the local school teacher but her background catches up with them.
Trampas is sent to collect the money from a cattle sale for ranchers at Medicine Bow. He receives the money in cash but events lead to a woman borrowing $1500 of it forcing Trampas and later Ryker to track her to recover the money.
The Virginian hires a man kicked off a cattle drive by the trail boss even though he is half owner of the herd. The herd passing Shiloh is suspected of having Spanish Fever. The man returns to the herd but his immaturity creates problems.
Ryker's chess playing friend's bride he met in San Francisco arrives but unknown to him she has a hidden past she hides with a bottle. At the same time two brothers released from prison visit Ryker wanting revenge for their dead brother.
The naive Randy is tricked into helping rob a bank in Kansas and due to circumstances is accused by a respected sheriff of being involved in the robbery. The Virginian is left on his own to prove Randy's innocence versus the sheriff.
A crusty timber man threatens the ranchers' grazing lands by clear cutting. He and his foreman expect his daughter to marry the foreman but she has second thoughts when a rancher's son shows an interest in her resulting in a killing.
Trampas escorts a murderer back to a town where he knew the sheriff. There is a question of the man's innocence plus Trampas learns the sheriff died in a horse accident two days later. He decides to investigate the questionable stories.
The Virginian goes to Honesty, Wyoming to collect $8000 owed the Judge on a crooked cattle deal. The town is owned and run by the corrupt man who owes the money. The fight over the money spills into a murder charge against the Virginian.
Trampas feeling sorry for an old cowboy and his grandson decides to hire him at Shiloh on his own. The old man complains about the way the other hands do their jobs but his mistakes and accidents proved costly to others and Shiloh itself.
The Virginian arrives in Monolith, Arizona to buy cattle from the Landers family but finds himself in the middle of a feud between them and the city Marshall Frome and his brother. The Fromes seem overbearing but maybe with a reason.it
This episode is a crossover with the Texas Rangers from the show Laredo. Trampas is sent by the Virginian to Mexico to return with a bull purchased by Judge Garth. While in Laredo waiting to cross over into Mexico, Trampas becomes involved in fights with three of the Texas Rangers. He ends up traveling with them into Mexico to recover money stolen from a train and to save a baby found alone on the train. This episode has a strong comedic bent to it.
Ryker must track down a close friend and his family after the man killed an Army guard while breaking his brother out of the stockade before being shot for dereliction. After they fight off Indians, the man is forced to face the law.
The Virginian accidentally kills the son of an Australian sheep rancher who has little time and love for his family. His daughter is in the middle between The Virginian who she loves and her father who barely notices her.
Rafe Simmons wants to learn to read so he can read his mother's diary. He quits Shiloh to move to Medicine Bow to learn from the attractive Martha Perry. However, the big man is caught in a tangle with town bullies and her ex-con husband.
In a mid life crisis Trampas decides to quit Shiloh when his vagabond friend arrives in Medicine Bow. The two head for Deadwood and excitement where a prospector takes them but his claim is on Indian land which is illegal and dangerous.
Betsy meets the broke minister David Henderson who is roaming the west looking for a calling after a turbulent history. He becomes involved with helping local miners fighting the mine management as well as Betsy who has found her calling.
Ryker is on a stage that is stopped by a group of Mexicans who are after one of the passengers for killing one of their women. The leader knows Ryker who is proposing they let the law settle the issue but the Mexicans want justice - now.
Judge Garth's niece Jennifer comes to live with him at Shiloh after her parents are killed in an accident. However, she is uncomfortable with her uncle who disapproved of her father. A young man she met seems to help but he has a past.
Ben Justin takes over a ranch next to Shiloh. He has had a string of bad luck including the death of his first wife. His son wants to help him but Ben keeps him and his wife Mary at arms length out of fear they will see the real Ben.
While returning to Shiloh Trampas injures his horse saving a man with a runaway team. He is forced to stay a few days in a small town with the man as an old friend arrives to force the town to sign over its gambling rights to him.
On a trip to Mexico with Trampas to pick up six palominos The Virginian becomes sick. He forced to stay at a lonely saloon and inn tended by the girl friend of a local outlaw. As he recovers she decides she would prefer life with him.
Widower Stavros Karas has agreed with a friend in Greece to marry his daughter. He told his friend he had a nice place but in reality he has little and needs water from his neighbor whose son falls for his young and beautiful bride.
Two tramps kill the wife of Ev Clinchy provoking the ire of Ev and his friend Hezekiah who want to lynch them. The sheriff keeps them at bay but when he is killed it is up to Ryker to protect the men against his close friends for trial.
A renown bronc buster is hired to break a group of rough mustangs at Shiloh. He picks Randy who is green to help him and Randy comes to idolize him as they break a black stallion. However, unknown to Randy there is a dark side to man.
A dying man clears a man sent to prison but the Governor and the railroad still believe he is guilty. He is paroled but still hounded by a railroad agent. When he is suspected of a second robbery, Ryker is not sure all is as it seems.it
A respected but retired Medicine Bow lawman is trying to make a living for him and his daughter on a farm but the bank is about to foreclose. A man involved in robbing a gold shipment offers him gold for hiding him out.