Fred wakens from a nap to hear Pebbles and Bamm-Bamm singing in tune and accompanying themselves on musical instruments--amazing, since they can't even talk yet. Famous manager Eppy Brianstone signs up the kids, and they become an overnight sensation. Wilma and Betty jet around to the kids' performances and Fred and Barney are largely left behind. On the eve of their departure for Eurock, Fred decides no one is going to deprive the babies of their childhood, contract or no contract.
Mrs. Slaghoople is threatening to move to Bedrock, so Fred wants to be sure he has a place of her own ready for his mother-in-law. He finds a likely house for sale and he and Barney begin renovations, while keeping the purchase of the house a secret from Wilma. As always, complications ensue.
Stoney Curtis is in town shooting a film. To promote it, a contest offers the prize of Stoney as slave for a day. Wilma and Betty win, and Fred sets Stoney to work as if he really were a slave. At Wilma's prompting, Stoney encourages Fred to believe that he himself could become a Hollyrock star, and Fred falls for the bait so seriously that he decides to put his house up for sale.
Fred is foreman of the jury trying "the Mangler," a vicious and enormous thief. When he is convicted, the Mangler swears to Fred's face that he'll "get you, Flintstone." Fred can't help being afraid, especially when word gets out that the Mangler has escaped from custody.
Who knew: the Stephens family of TV's "Bewitched" are the Flintstones' next-door neighbors. Fred and Barney go on a weekend camping trip, claiming that women can't rough it as they do. In response, Samantha takes Wilma, Betty, and the children camping, using her magical twitch of the nose whenever necessary to upstage the boys.
Introducing the Great Gazoo from Planet Zetox, sent to primitive Earth to redeem himself by aiding earthlings such as Barney and Fred. In his first encounter with the cavemen, he makes it possible for Fred to treat Wilma to dinner at the posh restaurant she's practically bribed him to take her to. But as Fred and Barney will discover, there's always a down side to Gazoo's generosity.
At the gravel pit's annual picnic, Fred is somewhat of a party pooper, unwilling to participate in the fun and games. He goes off by himself instead and finds a tree under which he falls asleep. He wakes to find the picnic over, and a good many changes besides. Barney has become an oil tycoon--and an old man; Pebbles and Bamm-Bamm are grown and married; and Wilma is an old lady whom Barney has taken in as a charity case. Has Fred slept his life away?
When the gravel pit's workers demand a raise, Mr. Slate gives it to them, using the savings from the salary of Fred, whom he fires. Fred, in need of income, finds he has a knack for making gravelberry pies. He succeeds with his confections so well at first that he becomes the "Gravelberry Pie King." But then the Great Gazoo intervenes, and, as usual, matters deteriorate from that point.
A secret organization wants to take over the world. To set their plan in motion, they intend to kidnap a professor, but, as the man is a dead ringer for Barney Rubble, they mistakenly target Barney instead. The Great Gazoo attempts to aid his "dumb-dumb" friends by lending Fred a James Bondrock-like sports car, but it will take more than the sophisticated vehicle to help the boys escape the bad men.
Fred and Barney have picked out the same costume for the Water Buffaloes' annual masquerade ball. Fred selects a new costume, determined to keep this one a secret. Inconveniently for Fred, his new costume, a space suit, debuts on the very night an "invasion of the Way-Outs" is announced in Bedrock, causing instant panic among the populace.
While waiting for tickets to a popular teen music show, Fred injures his leg, grabs it, and hops about on one foot. The surrounding teenagers dig this crazy new dance step. The "Flintstone Frantic" is an instant hit. Will Fred become an international star, teaching the Frantic even to world leaders such as LBJ and General de Gaulle?
Rockarabians seek the missing heir to their nation's throne. They know what he looks like: enough like Barney Rubble to be his twin. Ignoring his protests that they have the wrong fellow, the Rockarabians carry Barney bodily to the hotel at which their delegation is staying. Barney begins to think it might not be so bad to become an exotic monarch, until he is told he will have to select many beauties for his harem--something he knows Betty will never allow.
Betty and Wilma want to go out for the evening, while the boys want to practice for an upcoming bowling tournament. No problem: the Great Gazoo creates doubles of Barney and Fred. Or, more precisely, the doubles are the beginning of a big problem.
Fred has violent sneezing caused by an allergy. To stop the sneezing, he goes to the drug store for a bottle of "Scram." Each such pill stops a fit of sneezing, but has the side effect of turning Fred temporarily into an ape.
Fred borrows money from Mr. Slate to fix up his backyard for a long weekend. He plans to spend the whole weekend in Bedrock with his family and the Rubbles. But Gazoo invites the Rubbles and Flintstones to spend the weekend in the 25th Century A.D. instead. Among the many marvels they encounter: a descendant of Mr. Slate who still wants back the money Fred borrowed that weekend, plus interest.
At the races at Hollyrock Park, Fred and Barney wager on dinosaurs picked by the Great Gazoo. Gangsters take note of their success and kidnap the two friends so that they can make winning picks for them.
Traveling through the desert on their way to Rock Vegas, Fred and Barney fall prey to con men who have seeded the river with phony gold. When it turns out that the river contains real gold after all, the con men will do whatever it takes to oust the Flintstones and Rubbles from their claim.
When Fred chooses bowling over taking her to a ball, Wilma calls upon a rich, dashing old boyfriend to escort her to the ball instead. Fred ultimately decides to crash the ball later in the evening, escorting his own date--Barney, transformed into "Barbara" by the Great Gazoo.
The cavemen and their children meet "Dripper," a dolphin-like sealasaurus and star of a show at a marine park. Dripper is the target of an abduction plot. Thinking they have Dripper, the kidnappers instead abduct Barney, who's dressed in scuba gear.
Overhearing Wilma telling Betty that Dino has aristocratic ancestry, a member of the country club assumes it's Fred who's being spoken of, and invites the Flintstones to become members. Fred knows he's in need of polishing, but when the evening of the big event at the country club arrives, he and Wilma have an inspiration: go as themselves and show the snobs how to have a good time.