| Andy Griffith | ... | Sheriff Andy Taylor (249 episodes, 1960-1968) |
| Ron Howard | ... | Opie Taylor (210 episodes, 1960-1968) |
 | Frances Bavier | ... | Aunt Bee Taylor (175 episodes, 1960-1968) |
| Don Knotts | ... | Deputy Barney Fife / ... (141 episodes, 1960-1968) |
| George Lindsey | ... | Goober Pyle (86 episodes, 1964-1968) |
| Howard McNear | ... | Floyd Lawson (80 episodes, 1961-1967) |
| Aneta Corsaut | ... | Helen Crump (66 episodes, 1963-1968) |
| Colin Male | ... | Announcer / ... (66 episodes, 1960-1964) |
| Jack Dodson | ... | Howard Sprague / ... (38 episodes, 1966-1968) |
| Hal Smith | ... | Otis Campbell (32 episodes, 1960-1966) |
| Hope Summers | ... | Clara Edwards / ... (32 episodes, 1961-1968) |
| Betty Lynn | ... | Thelma Lou (26 episodes, 1961-1966) |
| Jim Nabors | ... | Gomer Pyle (23 episodes, 1962-1964) |
| Paul Hartman | ... | Emmett Clark (16 episodes, 1967-1968) |
| Mary Lansing | ... | Martha Clark / ... (15 episodes, 1962-1968) |
| Burt Mustin | ... | Jud Fletcher / ... (14 episodes, 1960-1966) |
| Robert McQuain | ... | Joe Waters / ... (14 episodes, 1961-1963) |
| Elinor Donahue | ... | Ellie Walker (12 episodes, 1960-1961) |
| Richard Keith | ... | Johnny Paul Jason / ... (12 episodes, 1962-1966) |
| Jack Burns | ... | Deputy Warren Ferguson / ... (11 episodes, 1965-1966) |
| Dick Elliott | ... | Mayor Pike (11 episodes, 1960-1962) |
| Joseph Hamilton | ... | A Townsman / ... (11 episodes, 1961-1964) |
| Sheldon Collins | ... | Arnold Bailey (9 episodes, 1966-1968) |
| Allan Melvin | ... | Clarence 'Doc' Mallory / ... (8 episodes, 1962-1967) |
| Dennis Rush | ... | Howie Pruitt / ... (8 episodes, 1963-1965) |
| Roy Engel | ... | A Townsman / ... (8 episodes, 1962-1968) |
| Howard Morris | ... | Ernest T. Bass / ... (8 episodes, 1963-1965) |
| Ronda Jeter | ... | Karen Burgess / ... (8 episodes, 1963-1966) |
| Parley Baer | ... | Mayor Roy Stoner (7 episodes, 1962-1963) |
| Charles P. Thompson | ... | Asa Breeney / ... (7 episodes, 1962-1967) |
| Denver Pyle | ... | Briscoe Darling (6 episodes, 1963-1966) |
| Maggie Peterson | ... | Charlene Darling Wash / ... (6 episodes, 1963-1968) |
| William Keene | ... | Reverend Hobart M. Tucker / ... (6 episodes, 1963-1968) |
| Norman Leavitt | ... | Wally / ... (6 episodes, 1960-1963) |
| Cheerio Meredith | ... | Emma Brand / ... (6 episodes, 1960-1962) |
| Jack Prince | ... | Rafe Hollister / ... (6 episodes, 1961-1963) |
| Forrest Lewis | ... | Angry man / ... (6 episodes, 1960-1964) |
| Janet Stewart | ... | Bernice / ... (6 episodes, 1962-1966) |
| Joy Ellison | ... | Betsy / ... (6 episodes, 1960-1967) |
| Doug Dillard | ... | Doug Darling / ... (6 episodes, 1963-1966) |
| Rodney Dillard | ... | Rodney Darling (6 episodes, 1963-1966) |
| Mitch Jayne | ... | Mitch Darling / ... (6 episodes, 1963-1966) |
| Dean Webb | ... | Dean Darling / ... (6 episodes, 1963-1966) |
| Amzie Strickland | ... | Myra Tucker / ... (5 episodes, 1960-1965) |
| Sherwood Keith | ... | Sam / ... (5 episodes, 1961-1962) |
| Warren Parker | ... | County Fair Judge / ... (5 episodes, 1961-1965) |
| George Cisar | ... | Cyrus Tankersley / ... (5 episodes, 1961-1967) |
| Frank Warren | ... | Art / ... (5 episodes, 1961-1962) |
| Ruth Thom | ... | Ella Carson / ... (5 episodes, 1966-1967) |
| Jason Johnson | ... | Mr. Weaver / ... (5 episodes, 1961-1967) |
| Olan Soule | ... | John Masters (5 episodes, 1962-1964) |
| Frank Ferguson | ... | Sam Lindsey / ... (5 episodes, 1960-1965) |
| Maudie Prickett | ... | Mrs. Larch / ... (5 episodes, 1964-1967) |
| Clint Howard | ... | Leon / ... (5 episodes, 1962-1964) |
| Sam Edwards | ... | Tom Bedlow / ... (5 episodes, 1960-1966) |
| Mabel Albertson | ... | Mrs. Sprague (4 episodes, 1966-1968) |
| Ken Lynch | ... | Captain Barker / ... (4 episodes, 1960-1967) |
| Jean Carson | ... | Daphne / ... (4 episodes, 1962-1965) |
| Dabbs Greer | ... | Councilman Dobbs / ... (4 episodes, 1961-1965) |
| Willis Bouchey | ... | Charlie O'Malley / ... (4 episodes, 1961-1964) |
| Dub Taylor | ... | Ben Beecham / ... (4 episodes, 1960-1968) |
| Ken Berry | ... | Sam Jones (4 episodes, 1968) |
| David Alan Bailey | ... | Trey Bowden / ... (4 episodes, 1964-1967) |
| Alberta Nelson | ... | Flora Malherbe / ... (4 episodes, 1966-1968) |
| Joanna Moore | ... | Peggy 'Peg' McMillan (4 episodes, 1962) |
| Josie Lloyd | ... | Josephine Pike / ... (4 episodes, 1961-1965) |
| Stanley Farrar | ... | County Fair Judge / ... (4 episodes, 1961-1965) |
| Phil Chambers | ... | Jason the Hotel Clerk / ... (4 episodes, 1960-1961) |
| Barbara Perry | ... | Doris Williams / ... (4 episodes, 1963-1966) |
| James Seay | ... | Agent Bowton / ... (4 episodes, 1963-1964) |
| Rance Howard | ... | Bus Driver / ... (4 episodes, 1962-1964) |
| Lee Krieger | ... | Merle Dean / ... (3 episodes, 1961-1963) |
| Bernard Fox | ... | Malcolm Merriweather (3 episodes, 1963-1965) |
| Jon Lormer | ... | Fletch Dilbeck / ... (3 episodes, 1962-1964) |
| Herbie Faye | ... | Eddie Blake / ... (3 episodes, 1965-1967) |
| George Dunn | ... | Pete / ... (3 episodes, 1960-1961) |
| Mike Steen | ... | Sergeant Miller / ... (3 episodes, 1960-1961) |
| Joyce Jameson | ... | Skippy (3 episodes, 1962-1965) |
| Tol Avery | ... | Ben Weaver / ... (3 episodes, 1964-1967) |
| Byron Foulger | ... | Fred, the hotel clerk / ... (3 episodes, 1965-1966) |
| Ray Lanier | ... | Bus Driver / ... (3 episodes, 1960-1962) |
| Jonathan Hole | ... | Orville Monroe (3 episodes, 1960-1961) |
| Lewis Charles | ... | Escaped Convict / ... (3 episodes, 1963-1965) |
| Carol Veazie | ... | Customer / ... (3 episodes, 1961-1967) |
| Dorothy Neumann | ... | Rita Campbell / ... (3 episodes, 1960-1962) |
| Owen Bush | ... | Doyle, the Clothier / ... (3 episodes, 1965-1967) |
| Jim Begg | ... | Charles Keyes / ... (3 episodes, 1966-1968) |
| John Reilly | ... | Billy (3 episodes, 1966) |
| Thom Carney | ... | Burly Peters / ... (3 episodes, 1961-1967) |
| Vince Barnett | ... | Elmo (3 episodes, 1967-1968) |
| Sara Seegar | ... | Gossip on Telephone / ... (3 episodes, 1960-1962) |
| Ronnie Dapo | ... | Arnold Winkler / ... (3 episodes, 1963-1966) |
| Molly Dodd | ... | Lillian / ... (3 episodes, 1963-1964) |
| Orville Sherman | ... | Billy Gordon / ... (3 episodes, 1961-1962) |
| Mary Treen | ... | Clara Lindsey / ... (3 episodes, 1960-1961) |
| Richard Collier | ... | Mr. Simmons / ... (3 episodes, 1966-1967) |
| Will Wright | ... | Ben Weaver (3 episodes, 1960-1962) |
| Robert Brubaker | ... | FBI agent Frank Brewster / ... (2 episodes, 1962-1965) |
| James Best | ... | Jim Lindsey (2 episodes, 1960-1961) |
| Richard X. Slattery | ... | Captain Dewhurst (2 episodes, 1967-1968) |
| Lurene Tuttle | ... | Annabelle Silby / ... (2 episodes, 1960-1964) |
| Tod Andrews | ... | Mr. Franklin / ... (2 episodes, 1961-1968) |
| Arlene Golonka | ... | Millie Hutchins (2 episodes, 1967) |
| Florence MacMichael | ... | Hilda Mae (2 episodes, 1960-1961) |
| Isabel Randolph | ... | Mrs. Bixby / ... (2 episodes, 1961-1963) |
| Al Checco | ... | Hennessey / ... (2 episodes, 1962-1965) |
| Jay Novello | ... | Attorney Neil Bentley / ... (2 episodes, 1962-1964) |
| Fred Sherman | ... | H. Fred Goss / ... (2 episodes, 1962) |
| Hoke Howell | ... | PFC Dudley A. 'Dud' Wash (2 episodes, 1963) |
| Paul Smith | ... | Army Doctor / ... (2 episodes, 1963) |
| Frank Cady | ... | Farley Upchurch / ... (2 episodes, 1965-1966) |
| David Ketchum | ... | Fred Michaels / ... (2 episodes, 1967) |
| Ruth McDevitt | ... | Mrs. Pendleton (2 episodes, 1968) |
| Ruta Lee | ... | Darlene Mason / ... (2 episodes, 1962-1965) |
| Robert Emhardt | ... | Malcolm Tucker / ... (2 episodes, 1963-1966) |
| Harlan Warde | ... | Mr. Williams / ... (2 episodes, 1963-1965) |
| Joey Scott | ... | Whitey Porter (2 episodes, 1963) |
| Virginia Sale | ... | Mrs. Beggs / ... (2 episodes, 1964-1966) |
| Charles Smith | ... | Counter Man / ... (2 episodes, 1965-1966) |
| Peter Hobbs | ... | Mr. Lockridge / ... (2 episodes, 1967-1968) |
| Don Keefer | ... | Carl Phillips / ... (2 episodes, 1967-1968) |
| Bill Erwin | ... | An investor / ... (2 episodes, 1960-1961) |
| Al Hopson | ... | Farmer / ... (2 episodes, 1961-1965) |
| Doodles Weaver | ... | George Bricker / ... (2 episodes, 1961-1963) |
| Larry Hovis | ... | Gilly Walker (2 episodes, 1965) |
| Richard Bull | ... | Bill Lindsay / ... (2 episodes, 1966-1967) |
| Claudia Bryar | ... | Jennie Boone / ... (2 episodes, 1961-1965) |
| Ross Elliott | ... | Al Saunders / ... (2 episodes, 1961-1965) |
| Terry Dickinson | ... | Sheldon / ... (2 episodes, 1961-1962) |
| Billy Halop | ... | Charlie / ... (2 episodes, 1963-1965) |
| Mary Jackson | ... | Miss Vogel / ... (2 episodes, 1964-1966) |
| Gavin MacLeod | ... | Bryan Bender / ... (2 episodes, 1965) |
| Ronnie Schell | ... | Bernie, the furrier / ... (2 episodes, 1966-1968) |
| Norman Alden | ... | Hank / ... (2 episodes, 1966-1967) |
| James McCallion | ... | Dr. Lou Bailey / ... (2 episodes, 1966-1967) |
| Maxine Semon | ... | Tillie Kincaid (2 episodes, 1966) |
| Richard Chambers | ... | Henny / ... (2 episodes, 1967) |
| Pat Colby | ... | Bill Matthews / ... (2 episodes, 1960-1963) |
| George Petrie | ... | Joe Layton / ... (2 episodes, 1961-1964) |
| Sally Mansfield | ... | Miss Fenwick / ... (2 episodes, 1962-1965) |
| Herb Vigran | ... | Bill Medwin / ... (2 episodes, 1962-1965) |
| Noreen Gammill | ... | A crusader / ... (2 episodes, 1963-1964) |
| Woody Chambliss | ... | Harlan Robinson / ... (2 episodes, 1965) |
| Jack Nicholson | ... | Marvin Jenkins / ... (2 episodes, 1966-1967) |
| Dick Poston | ... | Stage Manager / ... (2 episodes, 1968) |
| Ottola Nesmith | ... | Lady with jewelry / ... (2 episodes, 1962-1963) |
| William Christopher | ... | Dr. Thomas Peterson / ... (2 episodes, 1965-1966) |
| Arthur Malet | ... | Purvis / ... (2 episodes, 1966) |
| Buddy Foster | ... | Mike Jones (2 episodes, 1968) |
| Harry Antrim | ... | Fred Walker (2 episodes, 1960-1961) |
| Christine Burke | ... | Edna / ... (2 episodes, 1966-1967) |
| Edgar Hess | ... | Man / ... (2 episodes, 1966-1967) |
| Luana Anders | ... | Miss Clark (2 episodes, 1967) |
| Howard Hesseman | ... | Counterboy / ... (2 episodes, 1968) |
| Monty Margetts | ... | Maid / ... (2 episodes, 1967-1968) |
| Patty Regan | ... | Manicurist / ... (2 episodes, 1967-1968) |
| Anthony Jochim | ... | Harvey (2 episodes, 1967) |
| Diane Deininger | ... | Mrs. Briggs / ... (2 episodes, 1967-1968) |
| Hollis Morrison | ... | Alvin / ... (2 episodes, 1967-1968) |
| William Challee | ... | Checker Player / ... (2 episodes, 1960-1967) |
| Robert Williams | ... | Sam / ... (2 episodes, 1965-1967) |
| Peter Madsen | ... | Clerk / ... (2 episodes, 1967) |
| Tom Palmer | ... | Defense Attorney / ... (2 episodes, 1967) |
| Emory Parnell | ... | Juror / ... (2 episodes, 1967) |
| Charles Horvath | ... | Jenkins / ... (2 episodes, 1967-1968) |
| Mary Lou Taylor | ... | Mrs. Barton / ... (2 episodes, 1967-1968) |
| Reta Shaw | ... | Big Maude Tyler / ... (2 episodes, 1962-1964) |
| Sandy Kenyon | ... | George - History Teacher / ... (2 episodes, 1966-1967) |
| Kenneth Butts | ... | Arnie / ... (2 episodes, 1964-1965) |
| Elizabeth Harrower | ... | Mrs. Hutchins / ... (2 episodes, 1964-1967) |
| Jewel Rose | ... | Ladies' Aid Church Committee Member / ... (2 episodes, 1963-1964) |
| Don Wyndham | ... | Billy Hollander / ... (2 episodes, 1967) |
| Joseph Crehan | ... | Council member / ... (2 episodes, 1961) |
| Margaret Kerry | ... | Bess Muggins / ... (2 episodes, 1960-1961) |
| Billy Ray Latham | ... | Banjo Player (2 episodes, 1961) |
| Leroy Mack | ... | Guitar Player (2 episodes, 1961) |
| Clarence White | ... | Guitar Player (2 episodes, 1961) |
| Eric White | ... | Bass Player (2 episodes, 1961) |
| Roland White | ... | Mandolin Player (2 episodes, 1961) |
| Renee Aubry | ... | Choir Member (2 episodes, 1962-1964) |
| Delos Jewkes | ... | Glen Cripe / ... (2 episodes, 1962-1964) |
| Christopher Riordan | ... | Lead Charleston Dancer / ... (2 episodes, 1966-1967) |
