After saving the life of an Arapaho girl in a fire and helping acquit her in a trial for killing a man, Slim finds her his possession due to Arapaho law. When she won't leave him, he takes her in but soon finds he has feelings for her.
When Jess' horse is stolen, he tracks it and the thief, a young Mexican boy, to a town. The sheriff arrests the boy and Jess is forced to stay to testify only to learn the Judge is vindictive due to the murder of his son by a Mexican.
Slim is working as a range detective looking into cattle rustling after his ranch was hit. He finds out who may be doing the rustling. He catches one of them, a pretty girl, but not before she wounds him putting him in mortal danger.
Illiterate teenager Billy is caught between two drifters who want him to aid them in crime and Daisy along with Slim and reluctant Jess who try to teach and reform him. His only relative is a crusty uncle who wants nothing to do with him.
The husband of Slim's neighbor returns saying he has reformed and has a bank draft he wants to deposit but three men are chasing him for it. After saving Jess' life while working on a stage, they decide to help him but is all as it seems.
While looking for mustangs, Slim finds a small but somewhat tame one for Mike. That night someone steals the horse. Slim tracks it to a girl who owned the horse but also the middle of a potential range war between two groups over land.
Jess returning from a cattle sale helps a stranger caught in a gun battle who later trades identities with Jess when he is nearly killed in a saloon. Jess recovers but is mistaken for the stranger who is an outlaw but no one believes him.
Slim is acting sheriff when his neighbor's three outlaw step-brothers return looking for a place to rest and collect funds for their planned escape to Canada. Using his wife as a hostage they force him to help them with their plans.
Jess is in charge of a stage taking $50,000 from Laramie to Denver. A couple of outlaws develop a novel way of robbing the stage by blowing it up. Jess must track one of the outlaws who is wounded with the money to a strange setting.
Slim and Jess decide to go with Glen Colton to track a stage carrying his fiancé after the Sioux attack the relay station and go on the warpath. In their encounters Colton is never killed but almost captured raising questions with them.
Slim can provide an alibi for a man on trial for murder but when he returns at the request of the daughter to testify, they find him already hung. After being shot at he returns to find the daughter arrested for the murder of a witness.
Old memories surface when the officer in charge of Jess' POW camp turns up as the new deputy in Laramie. He tries to overcome the issue until other POWs arrive with revenge on their mind resulting in Slim and Jess against each other.
Old feelings revive when a woman Slim wanted to marry once returns to Laramie. She is there to sing in the casino her boyfriend is reopening after finishing a trip to prison. Her, her boyfriend and Sheriff Cory all have plans for Slim.
Jess finds himself in the middle of a potential marriage when he goes to help an older neighbor fight a range fire. He is asked to pick up the man's intended bride in Laramie but he soon determines she is not who she says she is.
Slim along with Daisy and Mike try to help a girl rescue her mother from a well when the woman's husband and two partners arrive. They have robbed the stage. The partners want to leave but slim tosses the money in with the woman.
Jess and Sheriff Cory find two of the three men who held up the Laramie bank and shot Mike. Before he dies one tells them they may find the third man Mitch in Chlorine. Jess must go alone but the reception in Chlorine is icy at best.
Slim's old CO is on a stage to Laramie with Jess riding shotgun. When he is wounded, he decides to stay at the Sherman ranch to rest and to size up political supporters who want him to run for President - expressing their views, however.
Slim's lack of attention opens his beautiful girlfriend Kitty to Vince Jackson who is a handsome, charming, fast gunman who has his sights set on her with extortion in mind from her father who owns the stage line and is Slim's boss.
Jess is acting deputy sheriff when he receives a note from his sister Francie who he thought was dead. He finds her in Laramie trying to get permission to bury her husband who is a well known outlaw but the townspeople won't allow it.
Young Virg Walker is being escorted back to Laramine by Slim when he's found using money from a stage robbery and murder. Although he puts up a fight on the return, something about him makes it seem unlikely he was part of the robbery.
Jess, injured by a falling tree in a dust storm, is nursed back to health by Sharon, daughter of a rancher plagued by rustlers. Sharon remains sympathetic to Jess even when the leader of the rustlers proves to be one of Jess's old friends.
With a $1000 prize there is stiff competition at the annual shooting contest in Laramie. Slim and Jess compete along with Slim's nemesis Rafe Seton and the young mountain man Hobie Carson. When Hobie wins, Rafe still wants the prize money.
Outlaw Al Denning, and his gang, are being chased by a posse led by Sheriff Cory and Jess, so he starts leaving behind some of the $25,000 in gold eagle coins behind to tempt the pursuing lawmen into a fight among themselves.
Slim is deputized to protect Stephen Collier, a murder suspect with a killer on his trail- and his lawyer, who's behaving very strangely. At same time a group of suffragettes arrives and the two events are related to everyone's surprise.
Jess is escorting a young boy to his father not knowing his mother wanted him with his aunt in Denver if she died. Once he tells Jess the truth he is determined to break away and go see his father, who is a cold blooded, murderous, outlaw.
When the son of neighbor is severely injured, a doctor at the Sherman Ranch is forced to help. However, the father wants revenge when the son's arm is amputated and he learns who the doctor is as he once arrested him.
Jess is deputy sheriff for the weekend while Sheriff Cory delivers some papers. Jess hopes to have a quiet weekend with only Parson Hawks as a prisoner and Mort's nephew Johnny who wants to be a deputy watching but things don't work out.