This was one of the first television shows to have its own original score and it was the first to feature modern jazz for a soundtrack. Previously, producers used generic music scores that were used in many television productions. RCA released an album of music from "Peter Gunn" featuring the title song and other pieces. It reached #1 on Billboard's chart, stayed there ten weeks, and stayed on the list for the next two years. It was so successful that RCA put together a sequel. Henry Mancini received an Emmy nomination for the theme and won two Grammys for the album.
The pianist who played the well known piano portion of the "Peter Gunn Theme" was future film composer John Williams.