Much of this film was shot at the famous "Old Tucson" facility, not far from the real Tombstone. However, its "town street" set was used surprisingly as Fort Griffin, Texas, in the opening reels, while later Tombstone street scenes were shot in southern California, on the same Paramount Ranch set that was later used as Virginia City, Nevada, on TV's Bonanza.
The actual gunfight took place on 26 October 1881 and lasted a mere 30 seconds, resulting in three dead men after an exchange of 34 bullets. Compared to this adaptation, the movie gunfight took 4 days to film and produced an on-screen bloodbath that lasted 5 minutes.
In his 1988 autobiography, The Ragman's Son, Kirk Douglas wrote that while playing Doc Holiday, he planned exactly how many and what kinds of coughs he would have in each scene so that continuity wouldn't be a problem once the film was edited together.