Jim and his foreman, Jeb Gaine, are busy moving onto the ranch purchased from Ovie and her two lovely daughters when the Wells Fargo agent is called back to service to retrieve plates used to counterfeit bonds. Hardie learns the plates were stolen by a group of former Confederate soldiers who plan to print enough worthless bonds that the United States economy would fall into shambles.
Acting on a tip that an outlaw gang may attack a gold shipment, Hardie and McCloud try to persuade group of stagecoach passengers to take the next stage so they can better protect the cargo. Each passenger has their own reasons for continuing the dangerous journey, and Hardie fears that the reasons of more than one are highway robbery.
Ex-convict Davey Hewitt is thrown off the train in Gloribee. He meets two members of his old outlaw gang who try to convince him to join them in robbing a bank that contains a large gold shipment for Wells Fargo. Meanwhile Jessamie, the handicapped daughter of Hewitt's new employer tries to convince him to go straight.
Hardie negotiates a new stagecoach route through Indian land with the local chief who is satisfied with the outcome. The tribe's young men, led by the warrior Red Knife, are looking for an excuse to return to the warpath.
Two gunmen rob a Wells Fargo train compartment and then hide the money in the baggage of a fellow passenger, a clown who stage name in Mr. Mute. When the clown unexpectedly decides to disembark from the train in Gloribee to perform at the town fair, the criminals must scramble to retrieve their ill-gotten loot before the money bags are discovered.
Jeremiah Logart, a former friend of Hardie's, is prevented from robbing a Wells Fargo office by Jim and his men. After a gun battle, Jim and Beau pursue of the remaining gang members and trail Jeremiah to the remote ranch of a widow and her two young children.
The estranged wife of a washed-up boxer returns to Gloribee to obtain custody of the couple's only child. Needing quick cash for legal fees, the boxer challenges the Frisco Kid, an up-and-coming pugilist, to a fight and wins, only to discover that the fight was fixed so that the Kid's crooked manager and his stooge could clean-up on side bets.
Hardie and McCloud capture Matt Blackner, an aging outlaw who is suffering from heart disease. He agrees to turn the money he stole from a Wells Fargo stagecoach if he's allowed to visit his wife and daughter before he's thrown in prison. Blackner's last days aren't to be happy ones - his wife is dead, his daughter despises him and his former gang members are trailing him to get their share of the hidden loot.
A veteran Wells Fargo stationmaster, about to retire, never gets the chance when two thieves stab him in the back and ransack the safe. Hardie suspects the killer is a part-time employee who disappeared after the robbery; Caleb Timmons and his sons want to find the man, too, since he ran off with Caleb's wife.
Three dance hall girls are being transported to Nevada to serve as witnesses in the murder investigation of a Wells Fargo agent. The subject of the investigation has no desire for the girls to testify and goes to great lengths to see that they don't arrive, including raiding Jim Hardie's ranch where the women are staying pending suitable escort.
Jamie Coburn, a member of Birch Morgan's notorious outlaw gang, agrees to turn himself in and help capture Wells Fargo capture the outlaw leader. Hardie allows the gunslinger to visit his ailing mother, but when Jamie returns home he learns his mother has died and his wife wants nothing to do with him in spite of the hefty reward Wells Fargo has paid for Jamie's assistance.
Frank Lambert is furious when his kid brother, Wally, rides into his camp asking that the older man return the money he stole from Wells Fargo. He becomes even angrier when he learns that Jim Hardie followed Wally to arrest him. Meanwhile, Jeb Gaine becomes upset when his friends and neighbors lavish affection on him on his 60th birthday.
A former governor of a Mexican province flees to San Francisco with his family's money to buy guns for the revolutionaries. A gang of former Mexican soldiers operating with stolen papers plan to steal the money with the unwitting assistance of Wells-Fargo.
An old flame of Jim Hardie's, now a famous concert singer, returns to California on a concert tour. The singer's father knows his daughter still carries a torch for Hardie and wants her to decide once and for all whether she'll be a chanteuse or a rancher's wife. Meanwhile her maid plots to steal her employer's fabulous collection of jewelry.
Jeb's brother, Sergeant Gaine, discovers that three of his men have been falsely convicted in a drumhead court-martial for desertion to cover up for their commanding officer's illegal attack on a band of Piute Indians that resulted in the deaths of Wells Fargo stagecoach passengers. Hardie and Prentiss, the governor's agent, must act quickly to save the condemned men before Colonel Bledsoe can silence the potential witnesses against him by executing the soldiers.
Katherine Murdock, a writer from New England, is hired by Wells Fargo to write a series of articles about the West and her first research stop is in Gloribee. Hardie discovers that she had already made up her mind that the West is nothing but a violent wasteland and a series of brushes with lawlessness does little to change her attitude. It takes chance meeting with a honorable outlaw for her to consider altering her preconceived notions.
An ex-convict burning with the desire to avenge himself upon a judge who he insists falsely convicted him takes over a way-station and hijacks the stagecoach that Jim Hardie and an assortment of passengers are traveling in.
Hardie investigates a stagecoach hold-up and discovers only a single letter was stolen. He learns that the letter was sent from a woman who fled an arranged marriage with a brutal land baron to an itinerant painter. The two men race to find the woman first - the painter to marry her and the land baron to disfigure his ex-fiancée.
Cattle drovers waiting to deliver their beef to the railhead at Gloribee are making life miserable for the townspeople, but Jim Hardie won't accept the stock until they're cleared by a veterinarian. The local doctor died under suspicious circumstances and Hardie convinces his son, also a vet, to examine the stock and help solve the older man's death.
A blizzard forces the stagecoach in which Jim, Jeb and Tina are traveling to seek shelter in a ghost town. Investigating a light shining in the building that formerly served as the town's hotel, the passengers discover the town's last two residents barricaded against the expected onslaught of an escaped prisoner who is out for revenge.
Hardie hires The Great Reardon, a mind-reading act, to serve as the entertainment at Wells Fargo's 15th anniversary celebration. Reardon's act always involved trickery, but now he plans to use his wife's "powers" to swindle a mine owner out of $10,000 by claiming to be able to reveal the location of a missing vein of gold ore.