Jim gets shot, and finds himself recovering from his wound in the mansion of a wealthy family. However, one of the young women who is treating him asks him not to identify the person who shot him. Jim sets out to find out why.
During negotiations to purchase cotton, Bowie discovers that much of the cotton farm's labor is provided by the local prison comandante who keeps order by the crack of his whip and who is providing the labor in exchange for supposed donations to the church. However, his plan to expose the comandante as a thief takes a dangerous turn.
Bowie and an Indian friend make up a wild story to trick a crooked storekeeper who is cheating Bowie's friend Sam McCullers but their plan backfires. Bowie then enlists Sam's daughter, Rachel, in an attempt to clean up the mess.
While in San Antonio, Bowie obtains a map to a lost Spanish silver mine in Apache territory. However, seeking the mine could jeopardize peaceful relations with the local Lipan Apaches who also act as a buffer against the Comanches.
A family of backwoods grifters capture Bowie and convince him to pay them a dowry in exchange for not marrying the family's daughter. Bowie and his cousin try to recoup the money but their plan goes awry.
Bowie thinks he's pulling a joke on an Englishman who makes an offer to buy his "bear repellent", but the joke backfires and he winds up serving as the man's valet, and two men riding with them have other plans---to obtain the man's gold.
Bowie purchases a horse from an old friend for Ursula, the daughter of his business partner and future Mrs. Bowie. Unbeknownst to Bowie, his friend has stolen the horse from the wife of the local Lipan Apache chief.
Bowie joins the Lipan Apache tribe. He helps them in their war with the Comanches who are assisted by Bowie's old horse trading friend, Cephas. The Apaches agree to take a blindfolded Bowie to their lost silver mine but Cephas follows them.
Bowie returns to Louisiana to organize an expedition to rediscover and develop the Apache silver mine in Texas. He meets a young army lieutenant, Jeff Davis, who is interested in his plan. However, Jeff's older brother Joe has less adventurous plans for his younger brother.
A plantation owner will sell his plantation to Bowie but the price is a rare Venetian painting. The painting's owner is willing to sell but the painting is stolen, held for ransom and, unbeknownst to Bowie, duplicated.
Federal government tells Choctaw tribes to move from Mississippi to Arkansas. One tribe refuses because chief's son is sick. As Bowie guides a doctor to examine the boy, they encounter a young couple who are about to deliver a baby.
While visiting Tennessee, local politicians enlist Bowie's help in defeating Davy Crockett for Congress. Bowie agrees to help them but then refuses their smear tactics. When Bowie threatens to expose their scheme, they take him prisoner.
On the trail, Bowie rescues a sole surviving baby from a burning covered wagon. When the local sheriff refuses to get involved, a tavern owner agrees that she will watch the baby while Bowie tries to find a family willing to adopt.
A Creole aristocrat, with substantial land holdings in New Orleans, loses heavily at the crap tables. When he refuses to honor his IOU, Bowie offers him a partnership to develop the land in exchange for canceling the debt.
Reporter Tebbs asks Jess Miller to travel to San Antonio and retrieve $7,000 for Bowie. In route, Miller is mistaken for Bowie, first by bandits whose leader needs his help and then by a corrupt colonel who wants the money and pits the bandit leader against Miller in a fight to the death.