Joan Crawford, after receiving critical praise for her performance in A Woman's Face (1941), at one point campaigned for the role of the mute girl played by Dorothy McGuire. Crawford also owned the rights, but MGM studio chief Louis B. Mayer vehemently opposed the idea, telling her "No more cripples or maimed women".
While this film was based on Ethel Lina White's 1933 novel "Some Must Watch," there are several major differences. In the novel, the maid stalked by the killer was not mute. It was also set in contemporary England, not early 1900's New England. Finally, the title of the film and the idea of incorporating a "spiral staircase" as a thematic element comes from another source entirely: Mary Roberts Rinehart's 1908 novel "The Circular Staircase." The heroine of the book was not mute or crippled, nor were any of the murderer's victims.