After his definitive performance in Scarface (1932), Paul Muni vowed never to play a gangster again. This tactic worked well for a couple of years, with an Academy Award for The Life of Emile Zola (1937) and an Oscar nomination for The Story of Louis Pasteur (1936), but eventually the good parts started to dwindle. By 1946, Muni was keen to play a major role again, so took the part of a gangster in this film.
The film's original title was "Me and Satan" but producer Charles R. Rogers decided to change it to Angel on My Shoulder (1946) on the conclusion that no one would want to go to see a film about the Devil.
The failure of the original copyright holder to renew the film's copyright resulted in it falling into public domain, meaning that virtually anyone could duplicate and sell a VHS/DVD copy of the film. Therefore, many of the versions of this film available on the market are either severely (and usually badly) edited and/or of extremely poor quality, having been duped from second- or third-generation (or more) copies of the film.