The producers' reaction to the gag of Bugs responding to a hunter pointing a gun at him with a confident casual remark, "What's up, Doc?" was so favorable that they decided to make that a standard element of future films featuring the character.
There are at least two conflicting stories as to who came up with the "What's up, Doc?" line. Tex Avery claimed that he based the line on an expression used by his friends in Texas. However, Mel Blanc claimed that it was an ad-lib that he came up with while recording the dialogue.
Previously reported here: despite being the debut of Warner Bros.' most famous cartoon character, Bugs Bunny, this short was not included in any of the 6 annual Golden Collection DVD box sets when they were released from 2003 to 2008. However, one of the features on Volume 3 of the Golden Collection is a tribute to Bugs Bunny called: What's Up Doc? A Salute to Bugs Bunny. In this tribute A Wild Hare is shown in its entirety.