Shown at some engagements with Warner Bros.' new Vitasound audio process. Often incorrectly called a stereophonic process, Vitasound actually combined a standard, variable-width monophonic soundtrack with a second variable-width control track, located between the soundtrack and the sprocket holes, that increased loudness for certain scenes by switching on additional amplifiers and speakers. "Santa Fe Trail" was one of only two films shown in the Vitasound process (the other was Four Wives (1939)).
The song "Benny Havens, Oh!" (sung by the soldiers at the farewell party at Fort Leavenworth) is a song from West Point. Benny Havens ran a public house near by West Point Military Academy. The writing of the song in his establishment by a Lt. O'Brien is commemorated in a mural in the Benny Havens Room of the West Point Army Mess.
The failure of the original copyright holder to renew the film's copyright resulted in it falling into public domain, meaning that virtually anyone could duplicate and sell a VHS/DVD copy of the film. Therefore, many of the versions of this film available on the market are either severely (and usually badly) edited and/or of extremely poor quality, having been duped from second- or third-generation (or more) copies of the film.