| Janet Gaynor | ... | Esther Victoria Blodgett, aka Vicki Lester |
| Fredric March | ... | Norman Maine |
| Adolphe Menjou | ... | Oliver Niles |
 | May Robson | ... | Grandmother Lettie |
| Andy Devine | ... | Daniel 'Danny' McGuire |
| Lionel Stander | ... | Matt Libby |
| Owen Moore | ... | Casey Burke, director |
| Peggy Wood | ... | Miss Phillips, Central Casting clerk |
| Elizabeth Jenns | ... | Anita Regis |
| Edgar Kennedy | ... | Pop Randall, landlord |
| J.C. Nugent | ... | Mr. Blodgett |
| Guinn 'Big Boy' Williams | ... | Posture coach (as Guinn Williams) |
| rest of cast listed alphabetically: |
| Eric Alden | ... | Assistant to Oliver Niles (uncredited) |
| Irving Bacon | ... | Station Agent (uncredited) |
| Jane Barnes | ... | Waitress #1 (uncredited) |
| Vince Barnett | ... | Otto, photographer (uncredited) |
| Clara Blandick | ... | Aunt Mattie (uncredited) |
| Wade Boteler | ... | Policeman at Santa Anita (uncredited) |
| Sidney Bracey | ... | Butler at Burke's party (uncredited) |
| Harry C. Bradley | ... | Assistant to Oliver Niles (uncredited) |
| Lynton Brent | ... | Reporter (uncredited) |
| Blanche Bush | ... | (uncredited) |
| Helene Chadwick | ... | Woman at preview (uncredited) |
| George Chandler | ... | Deliveryman (uncredited) |
| Billy Coe | ... | Bartender (uncredited) |
| Virginia Dabney | ... | (uncredited) |
| Billy Dooley | ... | Film crewman with spray gun (uncredited) |
| Dora Early | ... | (uncredited) |
| Herbert Evans | ... | Bartender at Burke's home (uncredited) |
| Pat Flaherty | ... | 'Cuddles', sanitarium guard (uncredited) |
| Francis Ford | ... | William Gregory, first defendant (uncredited) |
| Trixie Friganza | ... | Mabel, waitress #2 (uncredited) |
| Jean Gale | ... | (uncredited) |
| Joe Gray | ... | Garcia, boxer (uncredited) |
| Harrison Greene | ... | Chubby previewer (uncredited) |
| Carlton Griffin | ... | Cameraman (uncredited) |
| Jonathan Hale | ... | Night Court Judge George J. Parris (uncredited) |
| Sherry Hall | ... | Night Court clerk (uncredited) |
| Chuck Hamilton | ... | Policeman outside night courtroom (uncredited) |
| Lillian Harmer | ... | Wardrobe woman (uncredited) |
| Grace Hayle | ... | Woman in funeral mob scene (uncredited) |
| Edward Hearn | ... | Sanitarium attendant (uncredited) |
| Leon Holmes | ... | (uncredited) |
| Robert Homans | ... | Night Court bailiff (uncredited) |
| Kenneth Howell | ... | Milton Rails, second defendant (uncredited) |
| Olin Howland | ... | Judd Baker, motorist (uncredited) |
| Arthur Hoyt | ... | Assistant makeup artist (uncredited) |
| Mary Jane Irving | ... | (uncredited) |
| I. Stanford Jolley | ... | Boxing ringsider (uncredited) |
| Eddie Kane | ... | Guest at Burke's party (uncredited) |
| Matty Kemp | ... | Preview reporter (uncredited) |
| Claude King | ... | John, guest at Burke's party (uncredited) |
| Carole Landis | ... | Girl in beret at Santa Anita bar (uncredited) |
| Myra Marsh | ... | Assistant to Oliver Niles (uncredited) |
| Chris-Pin Martin | ... | José Rodriguez, last defendant (uncredited) |
| Edwin Maxwell | ... | Voice coach (uncredited) |
| Buddy Messinger | ... | Boy delivering fan mail (uncredited) |
| Willy Morris | ... | Niles' secretary (uncredited) |
| Ferdinand Munier | ... | Waiter at Burke's party (uncredited) |
| Marshall Neilan | ... | Bert, at Santa Anita clubhouse (uncredited) |
| David Newell | ... | Sam, at Santa Anita clubhouse (uncredited) |
| Robert Emmett O'Connor | ... | Bartender at Santa Anita clubhouse (uncredited) |
| Dennis O'Keefe | ... | Guest at Burke's party (uncredited) |
| Ted Oliver | ... | Policeman #2 at Santa Anita (uncredited) |
| Renee Orsell | ... | (uncredited) |
| Franklin Pangborn | ... | Billy Moon, radio commentator (uncredited) |
| Harvey Parry | ... | Boxer (uncredited) |
| Bob Perry | ... | Boxing match referee (uncredited) |
| Lee Phelps | ... | Bailiff #1 (uncredited) |
| Jed Prouty | ... | Artie Carver, columnist (uncredited) |
| Sally Raynor | ... | (uncredited) |
| Tom Ricketts | ... | Ray, Vicki's servant (uncredited) |
| Adrian Rosley | ... | Makeup artist (uncredited) |
| Kathryn Sheldon | ... | Funeral Spectator (uncredited) |
| Paul Stanton | ... | Academy Award presenter (uncredited) |
| Vera Steadman | ... | (uncredited) |
| A.W. Sweatt | ... | Aleck Blodgett, Esther's brother (uncredited) |
| Margaret Tallichet | ... | Marion, at Santa Anita clubhouse (uncredited) |
| Fred 'Snowflake' Toones | ... | Black man on witness stand (uncredited) |
| Lana Turner | ... | Extra at Santa Anita (uncredited) |
| Leonard Walker | ... | Orchestra leader at Hollywood Bowl (uncredited) |
| Luana Walters | ... | (uncredited) |
| Cynthia Westlake | ... | (uncredited) |
| Gayne Whitman | ... | Radio announcer at Grauman's Chinese Theater (uncredited) |
| Charles Williams | ... | Hanley, assistant cameraman (uncredited) |
| Clarence Wilson | ... | Justice of the Peace (uncredited) |
