Many scenes featuring Graf Orlok were filmed during the day, and when viewed in black and white, this becomes extremely obvious. This potential blooper is corrected when the "official" versions of the movie are tinted blue to represent night.
Ruth Landshoff, the actress who played the hero's sister, once described a scene in which she fled the vampire, running along a beach. That scene is not in any version of the film, nor in the original script.
Shadow of the Vampire (2000) is a fictionalised depiction of the events surrounding the film's production based on the urban legend that Max Schreck was in actuality a vampire. Schrek was played by Willem Dafoe in that film.
There have been different first names for the main characters in different English versions. In a few, Hutter is called "Thomas", in others is "Jonathon". Although Hutter's wife is credited as "Ellen", in some versions she is called "Mina".
Some footage of this film and another 1920's silent films, Battleship Potemkin and Dr. Jekyll and Mr. Hyde, were used in the British Rock Band, Queen's Music Video for "Under Pressure" with David Bowie sharing vocals.
The trivia items below may give away important plot points.
The concept in popular culture that sunlight is lethal to vampires is based on this film, which depicted such a death for the very first time in film history. F.W. Murnau knew that he would be sued for borrowing heavily from Bram Stoker's 1897 novel "Dracula" without permission, so he changed the ending in order that he could say that this film and "Dracula" were not exactly the same.