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- Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
- In Nazi-occupied France during World War II, a plan to assassinate Nazi leaders by a group of Jewish U.S. soldiers coincides with a theatre owner's vengeful plans for the same.
- Three buddies wake up from a bachelor party in Las Vegas, with no memory of the previous night and the bachelor missing. They make their way around the city in order to find their friend before his wedding.
- In a version of 1985 where superheroes exist, the murder of a colleague sends active vigilante Rorschach on the trail of a conspiracy that will change the course of history.
- A paraplegic Marine dispatched to the moon Pandora on a unique mission becomes torn between following his orders and protecting the world he feels is his home.
- A newly-possessed high-school cheerleader turns into a succubus who specializes in killing her male classmates. Can her best friend put an end to the horror?
- The early years of James Logan, featuring his rivalry with his brother Victor Creed, his service in the special forces team Weapon X, and his experimentation into the metal-lined mutant Wolverine.
- 78-year-old Carl Fredricksen travels to Paradise Falls in his house equipped with balloons, inadvertently taking a young stowaway.
- After being dumped by the girl he believes to be his soulmate, hopeless romantic Tom Hansen reflects on their relationship to try and figure out where things went wrong and how he can win her back.
- The brash James T. Kirk tries to live up to his father's legacy with Mr. Spock keeping him in check as a vengeful Romulan from the future creates black holes to destroy the Federation one planet at a time.
- A pushy boss forces her young assistant to marry her in order to keep her visa status in the U.S. and avoid deportation to Canada.
- A waitress, desperate to fulfill her dreams as a restaurant owner, is set on a journey to turn a frog prince back into a human being, but she has to face the same problem after she kisses him.
- The Feds try to take down notorious American gangsters John Dillinger, Baby Face Nelson, and Pretty Boy Floyd during a booming crime wave in the 1930s.
- In a dangerous post-apocalyptic world, an ailing father defends his son as they slowly travel to the sea.
- As Harry Potter begins his sixth year at Hogwarts, he discovers an old book marked as "the property of the Half-Blood Prince" and begins to learn more about Lord Voldemort's dark past.
- Wandering her rambling old house in her boring new town, an 11-year-old Coraline discovers a hidden door to a strangely idealized version of her life. In order to stay in the fantasy, she must make a frighteningly real sacrifice.
- While on tour in Afghanistan, Sam's helicopter is shot down and he is presumed dead. Back home, it is his screw-up brother who looks after the family. Sam does return, but with a lot of excess baggage.
- A teenager attends a fantasy writers' convention where he discovers his idea has been stolen by an established novelist.
- Mike O'Donnell is ungrateful for how his life turned out. He gets a chance to rewrite his life when he tried to save a janitor near a bridge and jumped after him into a time vortex.
- Detective Sherlock Holmes and his stalwart partner Watson engage in a battle of wits and brawn with a nemesis whose plot is a threat to all of England.
- A comedy set in a world where no one has ever lied, until a writer seizes the opportunity for personal gain.
- Violence ensues after an extraterrestrial race forced to live in slum-like conditions on Earth finds a kindred spirit in a government agent exposed to their biotechnology.
- In New York City's Harlem circa 1987, an overweight, abused, illiterate teen who is pregnant with her second child is invited to enroll in an alternative school in hopes that she can re-route her life in a better direction.
- A frustrated writer struggles to keep his family alive when a series of global catastrophes threatens to annihilate mankind.
- Brian O'Conner, back working for the FBI in Los Angeles, teams up with Dominic Toretto to bring down a heroin importer by infiltrating his operation.