30 May 2014 4:30 AM, PDT | Moviefone | See recent Moviefone news »

The comedy Western is a notoriously tricky genre to tackle, with only a few filmmakers (usually masters like Mel Brooks or Quentin Tarantino) actually able to pull it off. In recent years, big-budget Westerns, released in the summer, have even more difficulty getting off the ground -- just ask the makers of "Cowboys & Aliens" and "The Lone Ranger." (Is it still "too soon" to talk about "Wild Wild West"?) But none of this seems to have affected Seth MacFarlane, the co-writer, director, and star of "A Million Ways to Die in the West."

MacFarlane stars as a hapless sheep farmer who challenges Neil Patrick Harris to a duel. Harris is the new beau of MacFarlane's ex, played by Amanda Seyfried, a fancy man who owns a store that sells mustache oils. Of course, MacFarlane gets some much-needed advice (on both women and gun-slinging) from a mysterious stranger played by Charlize Theron, »

- Drew Taylor

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