Kristen Wiig will star in the Indian Paintbrush production about a cash-strapped woman who agrees to smuggle black market organs.
Rockwell will play her partner in crime, with Janney as her intimidating, polyamorous boss.
Rash and Faxon wrote the script and will also re-team with The Way Way Back producer Kevin J Walsh.
The Heart will begin shooting in North Carolina in May. »
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