With executive producers Damon Lindelof and Carlton Cuse joined by several members of the hit show's cast -- Josh Holloway, Jorge Garcia, Yunjin Kim, Ian Somerhalder, Maggie Grace, Henry Ian Cusick and Malcolm David Kelley -- secrets were sure to be revealed.
Here are 10 of the most important things learned at the panel:
1. Lindelof and Cuse know who shot at the outrigger, but they're not telling
One of the biggest mysteries of "Lost" comes from a Season 5 episode in which the time-traveling castaways find themselves in the near future. They board an outrigger canoe to travel more quickly but are quickly shot at by people in another boat.
"Lost" never explained who these people might be. But it turns out the writers know. They even wrote a scene in which the full explanation is given.