The two-minute video features clips from some of the studio's most famous films.
James Bond gets a special focus, with appearances from Daniel Craig, Sean Connery and Pierce Brosnan.
Thelma and Louise, Fargo, Some Like It Hot, Rain Man, The Good, the Bad and the Ugly, Silence of the Lambs and Rocky are also among the many projects spotlighted.
The video features Meg Ryan's famous fake orgasm scene from When Harry Met Sally as well.
Metro-Goldwyn-Mayer was founded in 1924 with the merging of Metro Pictures Corporation, Goldwyn Pictures and Louis B Mayer Pictures.