Jonathan Ross is once again hosting the awards, which will air live on Channel 4 next Thursday (December 12).
The Last Leg and its host Adam Hills lead the way with a total of three nominations.
Hills is in the running for Best Comedy Breakthrough Artist and Best Comedy Entertainment Personality, while The Last Leg is in contention to be named Best Comedy Entertainment Programme.
Jo Brand and Vicki Pepperdine are each nominated for their roles in NHS sitcom Getting On, which also receives a nod in the Best Sitcom category.
The Great British Bake Off's Mel and Sue are up against the likes of Miranda Hart and Sarah Millican for Best Female TV Comic.
Best New Comedy Programme will see competition from Count Arthur Strong,