The Les Misérables actress has entered negotiations for the Oscars host's latest live action movie A Million Ways to Die in the West, according to The Hollywood Reporter.
Seyfried would appear alongside Charlize Theron, assuming that deals are succesfully concluded for both.
A Million Ways to Die in the West features a meek farmer who backs out of a gunfight, breaking up with his girlfriend as a consequence.
He befriends the wife of an outlaw when she offers to teach him how to shoot, falling for her just as her husband reappears on the scene.
MacFarlane is planning to direct and star in the film, which is tipped to enter production in May.
Watch Amanda Seyfried talking »
Similar News ItemsCharlize Theron
- Are Sean Penn and Charlize Theron Engaged? (From Entertainment Tonight. 25 July 2014, 10:11 AM, PDT)
- "Mad Max: Fury Road" - What A Lovely Day (From SneakPeek. 25 July 2014, 8:24 AM, PDT)
- This Ring Isn't Helping Those Charlize and Sean Engagement Rumors (From Popsugar. 25 July 2014, 8:23 AM, PDT)
- Will These Summer Flings Go the Distance? (From Popsugar. 25 July 2014, 2:48 AM, PDT)
- First Images From While We’Re Young, Coming Home, Force Majeure, and A Second Chance (From Collider.com. 22 July 2014, 3:54 PM, PDT)
- Tiff '14: First Pictures from Noah Baumbach's 'While We're Young' (From Rope Of Silicon. 22 July 2014, 9:37 AM, PDT)
- 10 Cartoon Voices That Are Actually Impressions of Other Actors (From GeekTyrant. 24 July 2014, 11:00 AM, PDT)
- Bryan Cranston, Patrick Stewart and George Takei Lend Voices to ‘Family Guy’ Mobile Game (From The Wrap. 23 July 2014, 8:00 AM, PDT)
- Watch: Trailer For Sci-Fi Spoof 'Space Station 76' Starring Patrick Wilson, Liv Tyler And Matt Bomer (From The Playlist. 22 July 2014, 9:19 AM, PDT)