11 December 2012 9:28 AM, PST | Huffington Post | See recent Huffington Post news »

It's been a difficult year for Peter Krause, who plays Adam on NBC's "Parenthood" (Tuesdays at 10 p.m. Est). The actor has had to fight cancer both on screen with the series' most emotional Season 4 storyline, Adam's wife Kristina (Monica Potter) battling cancer, and off screen with his father and mother's simultaneous battle with the disease.

Krause opened up to HuffPost TV via phone about his personal connections to cancer, the fear of loss and finding the humor in the most difficult times. He also assures "Parenthood" fans that what looks like a harrowing Christmas episode this week is "uplifting ... in the end."

What was your reaction when you found out about the cancer storyline for Season 4?

It put a big lump in my throat. I lost my dad to cancer in February and my mom was diagnosed with cancer in December so she's been undergoing chemotherapy. So it's been »

- Jaimie Etkin

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