A spokesman for Aniston insists the rumours are false, although he has refused to rule out the possibility in the future.
The rep tells GossipCop.com, "At present there are no plans for Jennifer to be on the show. (But) never say never."
Aniston isn't the only former Friends star to turn down the offer - Matthew Perry refused to romance Cox for the new comedy in November.
But Cox shouldn't be too disappointed - Cougar Town, in which the star plays a middle-aged single mother on the hunt for a younger man, has been picked up for a second season by ABC network bosses.
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"Cougar Town" (2009)
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