The actress' mother was serving a federal prison sentence in Texas when she gave birth, and although baby Leighton was born in a halfway house, her mum returned to prison after her daughter turned three months.
According to America's Star magazine, Meester was raised by a relative while her mother completed time for her role in an illegal drug enterprise.
The publication also claims Meester's grandfather, father and aunt were jailed for drug dealing.
Meester's publicist was unavailable for comment when WENN went to press.
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