- Resigned from being a Victoria's Secret Angel to attend New York University.
- Loves baking and has a gluten- and dairy-free cookie line called Karlie's Kookies. Proceeds go to FEED Projects.
- She is of mostly German descent, along with one eighth Danish ancestry and a great-grandfather who was born in Poland.
- (October 18, 2018) Married her boyfriend of 6 years Joshua Kushner in a small, Jewish ceremony in upstate New York, with under 80 people in attendance. The pair announced their engagement in July, weeks after Kushner popped the question during a romantic weekend in upstate New York.
- Sister-in-law of Jared Kushner and Ivanka Trump.
- Was a ballet dancer.
- Daughter of Tracy and Kurt Kloss. Sister of Kristine, Kimberly and Kariann.
- Daughter-in-law of Charles Kushner and Seryl Kushner.
- Her first pregnancy with husband Joshua Kushner was announced on October 29th 2020 (via People Magazine).
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