- Daughter of Stephen (b. 1954) and Christina (née Molloy) O'Brien (b. 1955).
- Is the celebrity patron for the charity Animals in Distress Sanctuary.
- Was 4 months pregnant with her daughter Scarlett when she filmed her guest appearance on Blue Murder (2003).
- God-mother of Emily Walton who played her daughter on Coronation Street (1960).
- One of her favourite bands is Limp Bizkit.
- Joined Coronation Street (1960) on 31 October 1999 alongside Nikki Sanderson who played her character's best friend Candice Stowe.
- Attended Trinity Church of England High School, departing with nine GCSEs.
- Is a close friend of her Coronation Street (1960) co-star Jack P. Shepherd.
- Performed in the pantomime "Cinderella" as the titular role at Manchester Opera House (December 2007-January 2008).
- Was in a relationship with Coronation Street (1960) co-star Bruno Langley (2002-2003).
- Returned to work 13 months after giving birth to her daughter Scarlett in order to begin filming The Secret Diaries of Miss Anne Lister (2010).
- Competed on the 8th series of Strictly Come Dancing (2004), partnered with Jared Murillo, finishing 11th out of 14 celebrities.
- Her Coronation Street (1960) character Sarah-Louise Platt became the 13th woman on the soap opera to give birth. Sarah had a daughter Bethany (played originally by Amy Walton and Emily Walton and later Lucy Fallon), born on 4 June 2000, and sons Billy (played by an unknown baby), born on 1 June 2004, and Harry (played by an unknown baby), born on 21 March 2016.
- Was in a relationship with Ryan Thomas from 2003 to 2009. They have a daughter together.
- Has been in a relationship with personal trainer Adam Crofts since April 2011 and engaged since May 2016; they have a son together.
- Gave birth to her 1st child at age 25, a daughter Scarlett Jacqueline Thomas on October 26, 2008. Child's father is her now ex-boyfriend, Ryan Thomas.
- Gave birth to her 2nd child at age 31, a son Beau Lee Stephen Crofts on October 17, 2014. Child's father is her boyfriend, Adam Crofts.
- Returned to work 4 months after giving birth to her son Beau to begin filming on Coronation Street (1960).
- Is just 12 years older than Lucy Fallon, who plays her daughter on Coronation Street (1960).
- Maternal granddaughter of Joseph (1920-1992) and Christina (née Waterhouse) Molloy (1921-2002).
- Maternal great granddaughter of Joseph (1881-1943) and Lizzie (née Fletcher) Waterhouse (1884-1976).
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