Brian was born in the suburbs of Philadelphia, Pennsylvania. His mother is a retired school teacher and his father is a real estate broker. Brian has an older brother Jeffrey, a younger sister, Laurie and a younger brother, Michael. Brian went to Germantown Academy for high school and Carnegie Mellon University.

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Kelsey Grammer and Brian Klugman in Frasier (1993)

Kelsey Grammer, Peri Gilpin, and Brian Klugman in Frasier (1993)

Emily Deschanel and Brian Klugman in Bones (2005)

Cameron Douglas, Jake Hoffman, Brian Klugman, Chad Lindberg, and Branden Williams in Adam and Eve (2005)

Brian Klugman and Chad Lindberg in Adam and Eve (2005)

Agnes Bruckner, Brian Klugman, and Arjay Smith in Vacancy 2: The First Cut (2008)

Jason Rosen

Bradley Cooper and Zoe Saldaña in The Words (2012)

Sydney Greenbaum

Brian Klugman and Adrianne Palicki in Baby, Baby, Baby (2015)

Charlie

Jeff Bridges, Olivia Wilde, and Garrett Hedlund in Tron: Legacy (2010)

Brian Klugman

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