- Son of Amjad Khan.
- Was to debut in Vinod Khanna's Himalay Putra but later opted out. He was not happy with how Vinod Khanna was only concentrated on Akshaye Khanna in the film.
- Maternal grandfather Akhtar-Ul-Iman.
- Paternal grandfather Jayant.
- Nephew of actors Inayat Khan and Imtiaz Khan.
- Brother in law of actor Zafar Karachiwala ( Married to sister Ahlam).
- Brother Seemab Khan is a professional cricket player.
- Brother Seemab Khan works as a assistant director.
- Sister Ahlam Khan is a actress.
- Sometimes confused with an actor with the same name "Shadab Khan".
- Maternal uncle is actor Ramish Iman.
- Shadaab Khan published a book titled 'Murder in Bollywood' in 2015.
- Grand uncle Jehangir Khan was a assistant director in films in the 1930s. He passed away in a road accident in Mumbai shortly after arriving.
- Grand uncle is director N.K.Ziree.
- Debut film was Betaabi 1997.
- Returned to acting after 17 years in Romeo Akbar Walter in 2019.
- Aunt is Kruttika Desai wife of Imtiyaz Khan.
- Father Amjad Khan signed his iconic role of Gabbar Singh in Sholay 1975 the day he was born on 20 September 1973.
- Made is web debut in Sam 1992.
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