| AFI Awards, USA | |||
| Year | Result | Award | Category/Recipient(s) |
|---|---|---|---|
| 2002 | Nominated | AFI TV Award |
AFI Actor of the Year - Female - Series for: "Malcolm in the Middle" (2000) |
| American Comedy Awards, USA | |||
| Year | Result | Award | Category/Recipient(s) |
| 2001 | Won | American Comedy Award |
Funniest Female Performer in a TV Series (Leading Role) Network, Cable or Syndication for: "Malcolm in the Middle" (2000) |
| CableACE Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 1983 | Nominated | ACE |
Actress in a Dramatic Presentation for: "The Paper Chase" (1978) For episode "Outline Fever". |
| Emmy Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2006 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2005 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2004 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2003 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2002 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2001 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2000 | Nominated | Emmy |
Outstanding Lead Actress in a Comedy Series for: "Malcolm in the Middle" (2000) |
| Family Television Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2001 | Won | Family Television Award |
Actress for: "Malcolm in the Middle" (2000) Tied with Lauren Graham for "Gilmore Girls" (2000). |
| Golden Globes, USA | |||
| Year | Result | Award | Category/Recipient(s) |
| 2003 | Nominated | Golden Globe |
Best Performance by an Actress in a Television Series - Musical or Comedy for: "Malcolm in the Middle" (2000) |
| 2002 | Nominated | Golden Globe |
Best Performance by an Actress in a Television Series - Musical or Comedy for: "Malcolm in the Middle" (2000) |
| 2001 | Nominated | Golden Globe |
Best Performance by an Actress in a TV-Series - Comedy/Musical for: "Malcolm in the Middle" (2000) |
| Satellite Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2004 | Won | Golden Satellite Award |
Best Performance by an Actress in a Series, Comedy or Musical for: "Malcolm in the Middle" (2000) |
| 2002 | Nominated | Golden Satellite Award |
Best Performance by an Actress in a Series, Comedy or Musical for: "Malcolm in the Middle" (2000) |
| Screen Actors Guild Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2003 | Nominated | Actor |
Outstanding Performance by a Female Actor in a Comedy Series for: "Malcolm in the Middle" (2000) |
| 2001 | Nominated | Actor |
Outstanding Performance by a Female Actor in a Comedy Series for: "Malcolm in the Middle" (2000) |
| Teen Choice Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2002 | Nominated | Teen Choice Award |
TV - Choice Actress, Comedy for: "Malcolm in the Middle" (2000) |
| Television Critics Association Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2001 | Won | TCA Award |
Individual Achievement in Comedy for: "Malcolm in the Middle" (2000) |
| 2000 | Won | TCA Award |
Individual Achievement in Comedy for: "Malcolm in the Middle" (2000) |
| Viewers for Quality Television Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2000 | Nominated | Q Award |
Best Actress in a Quality Comedy Series for: "Malcolm in the Middle" (2000) |
| Young Artist Awards | |||
| Year | Result | Award | Category/Recipient(s) |
| 2004 | Nominated | Young Artist Award |
Most Popular Mom & Pop in a Television Series for: "Malcolm in the Middle" (2000) Shared with: Bryan Cranston |