- Epstein and brother Philip G. Epstein became the first twins to be awarded Oscars when they won in the writing category for Casablanca (1942).
- After the death of his twin brother in 1952, Epstein found working with a collaborator near impossible. He tried working with Billy Wilder three times, but nothing came of it.
- Great uncle of Anya Epstein and her brother Theo Epstein, general manager of the 2004 World Champion Boston Red Sox.
- The Epstein twins enjoyed a well-earned reputation, not only for writing witty dialogue, but also for coming up with the best impromptu wisecracks in the movie business.
- Was Penn State boxing team captain
- Twin brother of Philip G. Epstein.
- Woody Allen paid tribute to Epstein by using the name in two of his movies, once as character's license plate and in another as a character.
- Frank Capra recruited the Epstein Twins for a month's work on his Wartime informational series, "Why We Fight.".
- Epstein first arrived in Hollywood about 10:30 p.m. on Otctober 14, 1933 and by midnight was collaborating on the screenplay of "Twenty Million Sweethearts" as pages had to be turned in early Monday morning.
- Under contract to Warner Brothers from 1934 to 1944.
- Began in Hollywood in 1933 as ghostwriter for Jerry Wald. Considered himself the model for the character of Julian Blumberg in Budd Schulberg's novel 'What Makes Sammy Run?'.
- Epstein began learning how movies were made by observing how films were made on the set of "College Humor" with Bing Crosby.
- Graduated Penn State University (1931)
- Is the uncle of novelist Leslie Epstein ("Pandaemonium", "San Remo Drive")
- Two children, Elizabeth Schwartz and James.
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