Marion Cotillard was the first non-Belgian actor that him and his brother cast to lead one of their films. Cotillard is also the most famous actor to ever work with them. She was cast for Two Days, One Night (2014) after meeting the brothers on the set of Rust and Bone (2012), which was co-produced by them.
All of his films are set in Seraing, Liege, the Belgian town where him and his brother Jean-Pierre Dardenne were born and raised.
Four of his films have been chosen to represent Belgium for the Academy Award for Best Foreign Language Film: Rosetta (1999), The Son (2002), L'enfant (2005) and Two Days, One Night (2014), but none of them have ever been nominated, the only one that got an Oscar nomination is Two Days, One Night (2014), which was nominated for Best Actress.