Her partner Julie Cypher gave birth to two children, Bailey Jean (born in 1997) and Beckett (born in November 1998), which were adopted by Melissa.
Is a fan of Bruce Springsteen and the Dave Matthews Band.
Close friends with Brad Pitt.
Publicly revealed that David Crosby is the biological father of her two children with partner Julie Cypher, who gave birth to their children conceived through artificial insemination (January 2000).
Announced she is separating from long-time partner Julie Cypher (19 September 2000).
A close friend of Brad Pitt, two of his former girlfriends and his ex-wife appeared in her music videos: Juliette Lewis in "Come To My Window", Gwyneth Paltrow in "I Want To Come Over" and Jennifer Aniston in "I Want To Be In Love".
Ranked #49 on VH1's 100 Greatest Women of Rock N Roll
Ex-lover Julie Cypher left Lou Diamond Phillips to be with her.
Sang at Brad Pitt's and Jennifer Aniston's wedding
She and her girlfriend Tammy Lynn Michaels considers themselves as married since they exchanged vows in a secret ceremony in September 2003. Their marriage is not legally confirmed, because gay weddings are not legally binding in their home state California.
Was diagnosed with breast cancer (October 2004).
Made headlines when she gave a noteworthy performance at the 2005 Grammy Awards for the first time since being diagnosed with cancer; showing up bald from her chemotherapy treatments.
Announced in late 2005 that she is cancer-free and that she and partner Tammy Lynn Michaels are planning to have a child.
Announced that her longtime partner Tammy Lynn Michaels is pregnant and expecting twins (2006).
Her partner Tammy Lynn Michaels gave birth to a girl, Johnnie Rose, and a boy, Miller Steven, on 17 October 2006.
Gay rights and environmental activist.
Her father John died from cancer in 1992.
Although being famous for her smoky voice, she has never smoked and doesn't like whiskey.
Won two Grammy Awards for "Best Female Rock Performance" in 1992 and 1994.
Be strong, speak true and spread the peace.
"She has her own opinion. If people want to listen to it, that's fine...I don't believe in shutting anybody up." - (2000) about Dr. Laura Schlessinger's views against homosexuality
This is the only naked man that will ever be in my bedroom. [Backstage speaking to the media at _79th Annual Academy Awards, The (2007) (TV)_ on her win for Best Song, "I Need to Wake Up" for the documentary _An Inconvenient Truth (2006)_.] [25 February 2007]
(September 2001) Starting the "live...and alone" tour in support of her 2001 album "Skin"
(July 2008) On the road with the Revival Tour
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