Simon Doonan, Iman, Isaac Mizrahi, and Laura Brown in The Fashion Show (2009)

Iman, Isaac Mizrahi, and Laura Brown in The Fashion Show (2009)

Simon Doonan and Isaac Mizrahi in The Fashion Show (2009)

Iman and Isaac Mizrahi in The Fashion Show (2009)

Iman, Isaac Mizrahi, Johnny Weir, and Rachel Zoe in The Fashion Show (2009)

Mary J. Blige, Glenda Bailey, and Isaac Mizrahi in The Fashion Show (2009)

Mary J. Blige, Glenda Bailey, Iman, Isaac Mizrahi, and Laura Brown in The Fashion Show (2009)

Isaac Mizrahi and Heather Dubrow in Heather Dubrow & Isaac Mizrahi (2023)

Isaac Mizrahi and Dolores Catania in Dolores Catania & Isaac Mizrahi (2023)

Isaac Mizrahi and Sherri Shepherd in Sherri Shepherd & Isaac Mizrahi (2022)

Isaac Mizrahi and Eboni K. Williams in Eboni K. Williams & Isaac Mizrahi (2021)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Andrea Riseborough in All the World's a Runway (2019)

Isaac Mizrahi, Georgina Chapman, Andrea Riseborough, Irina Shabayeva, Dmitry Sholokhov, and Anne Fulenwider in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Andrea Riseborough, Irina Shabayeva, Dmitry Sholokhov, Michelle Lesniak, and Anne Fulenwider in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Andrea Riseborough, Evan Biddell, Irina Shabayeva, Dmitry Sholokhov, Michelle Lesniak, and Anne Fulenwider in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Andrea Riseborough, and Irina Shabayeva in All the World's a Runway (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Nina Garcia, and Iris Apfel in Nina Says Don't Cry Over Spilt Silk (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, Reem Acra, and Cynthia Erivo in Climate Quick Change (2019)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Asia Kate Dillon in Project Runway All Stars (2012)

Isaac Mizrahi and Asia Kate Dillon in Project Runway All Stars (2012)

Alyssa Milano, Isaac Mizrahi, and Georgina Chapman in Project Runway All Stars (2012)

Isaac Mizrahi and Georgina Chapman in Project Runway All Stars (2012)

Isaac Mizrahi, Georgina Chapman, Danica Patrick, and Wendy Williams in Project Runway All Stars (2012)

Isaac Mizrahi, Georgina Chapman, Peyton List, and Joan Smalls in Project Runway All Stars (2012)

Isaac Mizrahi, Rebecca Minkoff, and Olivia Culpo in Project Runway All Stars (2012)

Alyssa Milano, Debra Messing, Isaac Mizrahi, Georgina Chapman, and Anne Fulenwider in Project Runway All Stars (2012)

Alyssa Milano, Isaac Mizrahi, Georgina Chapman, and Nina Garcia in Project Runway All Stars (2012)

Isaac Mizrahi at an event for Extremely Loud & Incredibly Close (2011)

Isaac Mizrahi at an event for Sex and the City (2008)