(Best) Sci-Fi/Thriller/Mystery TV Shows

In no particular order... I've thrown a little crime in there too
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1.
Fringe (2008 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.5/10 X  
An FBI agent is forced to work with an institutionalized scientist and his son in order to rationalize a brewing storm of unexplained phenomena. (46 mins.)
 
2.
The Walking Dead (2010 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.6/10 X  
Sheriff Deputy Rick Grimes leads a group of survivors in a world overrun by the walking dead. Fighting the dead, fearing the living. (44 mins.)
 
3.
Taken (2002 Mini-Series)
Episode: Taken (2002)
    1 2 3 4 5 6 7 8 9 10 8.0/10 X  
Still being pursued by the military and by Mary Crawford, Lisa makes contact with her Uncle Tom who... (877 mins.)
 
4.
Falling Skies (2011 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.2/10 X  
Survivors of an alien attack on earth gather together to fight for their lives and fight back. (42 mins.)
“ Really good alien sci fi show :) Hard to find these days! Not the best CG though, but good enough storyline keeps me coming back :) ” - missrosepose
 
5.
Lost (2004 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.4/10 X  
The survivors of a plane crash are forced to work together in order to survive on a seemingly deserted tropical island. (44 mins.)
 
6.
Pretty Little Liars (2010 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.7/10 X  
Four friends band together against an anonymous foe who threatens to reveal their darkest secrets, while unraveling the mystery of the murder of their best friend. (60 mins.)
 
7.
Invasion (2005 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.6/10 X  
In the aftermath of a hurricane, a Florida Park Ranger and his family deal with strange occurrences... (60 mins.)
 
8.
The X-Files (1993 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.7/10 X  
Two FBI agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained while hidden forces work to impede their efforts. (45 mins.)
 
9.
Homeland (2011 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.4/10 X  
A bipolar CIA operative becomes convinced a prisoner of war has been turned by al-Qaeda and is planning to carry out a terrorist attack on American soil. (55 mins.)
 
10.
Caprica (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.1/10 X  
Two families, the Graystones and the Adamas, live together on a peaceful planet known as Caprica, where a startling breakthrough in artificial intelligence brings about unforeseen consequences. A spin-off of the Sci Fi Channel series "Battlestar Galactica" set 50 years prior to the events of that show. (60 mins.)
 
11.
Criminal Minds (2005 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.2/10 X  
The cases of the FBI Behavioral Analysis Unit (BAU), an elite group of profilers who analyze the nation's most dangerous serial killers and individual heinous crimes in an effort to anticipate their next moves before they strike again. (42 mins.)
 
12.
Outcasts (2010 TV Series)
    1 2 3 4 5 6 7 8 9 10 6.6/10 X  
With Earth rapidly becoming uninhabitable, pioneers seek to colonize the harsh terrain of the planet Carpathia. 10 years later, the town of Forthaven faces danger as the planet's dark secrets are revealed. (50 mins.)
“ I thoroughly enjoyed this BBC TV Series, the storyline was very well written, It was such a shame it never returned... :( ” - missrosepose
 
13.
Once Upon a Time (2011 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
A young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed. (44 mins.)
Director: David Barrett
 
14.
Continuum (2012 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.7/10 X  
A detective from the year 2077 finds herself trapped in present day Vancouver and searching for ruthless criminals from the future. (45 mins.)
 
15.
Flashforward (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.6/10 X  
A special task force in the FBI investigates after every person on Earth simultaneously blacks out and awakens with a short vision of their future. (42 mins.)
 
16.
Kyle XY (2006 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.6/10 X  
A family takes in a formerly institutionalized teen savant who is missing standard human behaviors such as anger, joy and love. (60 mins.)
 
17.
Firefly (2002 TV Series)
    1 2 3 4 5 6 7 8 9 10 9.1/10 X  
Five hundred years in the future, a renegade crew aboard a small spacecraft tries to survive as they travel the unknown parts of the galaxy and evade warring factions as well as authority agents out to get them. (44 mins.)
 
18.
United States of Tara (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
A woman struggles to find a balance between her dissociative identity disorder and raising a dysfunctional family. (30 mins.)
 
19.
Waking the Dead (2000 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
Detective Superintendent Peter Boyd is the leader of a police team which investigates unsolved murders using modern technology. (100 mins.)
 
20.
Roswell (1999 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.5/10 X  
The lives of three young alien/human hybrids with extraordinary gifts in Roswell. (42 mins.)
 
21.
Misfits (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.3/10 X  
A group of young offenders doing community service get struck by lightning during a storm, and begin to develop superpowers. (60 mins.)
 
22.
V (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 6.8/10 X  
An extraterrestrial race arrives on Earth with seemingly good intentions, only to slowly reveal their true machinations the more ingrained into society they become. (42 mins.)
 
23.
Dark Angel (2000 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.4/10 X  
A group of genetically-enhanced children escape from a lab project. Years later we meet Max, one of the escapees who now works for a messenger service in the post-apocalyptic Pacific Northwest. (60 mins.)
 
24.
Revenge (2011 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
An emotionally troubled young woman makes it her mission to exact revenge against the people who wronged her father. (44 mins.)
 
25.
Bones (2005 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
Forensic anthropologist, Dr. Temperance "Bones" Brennan, and cocky FBI special agent Seeley Booth build a team to investigate murders - and quite often, there isn't more to examine than rotten flesh or mere bones. (40 mins.)
 
26.
SGU Stargate Universe (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.7/10 X  
Trapped on an Ancient spaceship billions of light years from home, a group of soldiers and civilians struggle to survive and find their way back to Earth. (43 mins.)
 
27.
Terra Nova (2011 TV Series)
    1 2 3 4 5 6 7 8 9 10 6.8/10 X  
Centers on the Shannons, an ordinary family from 2149 when the planet is dying who are transported back 85 million years to prehistoric Earth where they join Terra Nova, a colony of humans with a second chance to build a civilization. (46 mins.)
 
28.
American Horror Story (2011 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.2/10 X  
An anthology series that centers on different characters and locations, including a house with a murderous past, an insane asylum, a witch coven, a freak show, and an enigmatic hotel. (60 mins.)
 
29.
Nikita (2010 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.7/10 X  
A rogue assassin returns to take down the secret organization that trained her. (60 mins.)
 
30.
Buffy the Vampire Slayer (1997 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.2/10 X  
A young woman, destined to slay vampires, demons and other infernal creatures, deals with her life fighting evil, with the help of her friends. (44 mins.)
 
31.
Smallville (2001 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.5/10 X  
A young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville. (60 mins.)
 
32.
Prison Break (2005 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.5/10 X  
Due to a political conspiracy, an innocent man is sent to death row and his only hope is his brother, who makes it his mission to deliberately get himself sent to the same prison in order to break the both of them out, from the inside out. (44 mins.)
 
33.
Supernatural (2005 TV Series)
    1 2 3 4 5 6 7 8 9 10 8.6/10 X  
Two brothers follow their father's footsteps as "hunters" fighting evil supernatural beings of many kinds including monsters, demons, and gods that roam the earth. (44 mins.)
 
34.
True Blood (2008 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
Telepathic waitress Sookie Stackhouse encounters a strange new supernatural world when she meets the mysterious Bill, a southern Louisiana gentleman and vampire. (55 mins.)
 
35.
Awake (2012 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.9/10 X  
After a car accident takes the life of a family member, a police detective lives two alternating parallel lives, one with his wife and one with his son. Is one of his "realities" merely a dream? (43 mins.)
 
36.
Surface (2005 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.2/10 X  
A marine biologist, an insurance salesman and a teen-aged boy find their lives fundamentally changed by the emergence of a new, and often dangerous, species of sea life, while government agents work to keep the affair under wraps. (60 mins.)
 
37.
Defying Gravity (2009 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.3/10 X  
Eight astronauts living aboard an international spacecraft on a mission through the Solar System, as the world watches from billions of kilometers away. (60 mins.)
“ I'll let you know once I've watched it :) ” - missrosepose
 
38.
Survivors (2008 TV Series)
    1 2 3 4 5 6 7 8 9 10 7.6/10 X  
An unknown virus pandemic kills more than 90% of the world's population. Those immune must strive to survive and overcome the difficulties of this new world order, hoping that the virus will not mutate. (60 mins.)